Prof. Dr. ŞERMİN GENÇ

Yayın Ağı

Makaleler 131

1. Intranasally delivered colostrum-derived small extracellular vesicles mitigate acute neuroinflammation in periventricular leukomalacia

Ture B., Erdogan F., Armagan C., Tastan B., Gonul C. P., Guducu Y., et al.

BRAIN RESEARCH , cilt.1870, 2026 (SCI-Expanded, Scopus)

2. Long non-coding RNA NEAT1 modulates microglial NLRP3 inflammasome activation

Tastan B., Cotuk A., Arioz B. I., Karacicek B., Ture B., Tastan N., et al.

Journal of Neuroimmunology , cilt.409, 2025 (SCI-Expanded, Scopus)

3. Altered NRF2 signalling in systemic redox imbalance: Insights from non-communicable diseases

Jakubowska M., Costa V. M., Krzeptowski W., Dominkus P. P., Santos M., Demirdogen B. C., et al.

REDOX BIOLOGY , cilt.87, 2025 (SCI-Expanded, Scopus)

4. Microglial NLRP3 inflammasome activation leads to perineuronal net loss in cocultured neurons.

Tarakcioglu E., Tüfekci K. U., Genc Ş.

Molecular biology reports , cilt.52, sa.1, ss.1023, 2025 (SCI-Expanded, Scopus)

5. Characterization of tRNA-derived fragments in the small neuron-derived extracellular vesicles of Alzheimer's disease patients

Arioz B. I., Binokay L., Tastan B., Genc B., Cotuk A., DURSUN E., et al.

Brain Research , cilt.1862, 2025 (SCI-Expanded, Scopus)

6. NLRP3 inflammasome: a key player in neonatal brain injury

Kiser C., Ercan I., Engur D., GENÇ Ş.

Clinical and Experimental Pediatrics , cilt.68, sa.7, ss.475-485, 2025 (ESCI, Scopus)

7. Neonatal NLRP3 Inflammasome Activation Leads to Perineuronal Net Deficits in Early Adulthood

Tarakcioglu E., Genc B., Tufekci K. U., GENÇ Ş.

Developmental Neurobiology , cilt.85, sa.3, 2025 (SCI-Expanded, Scopus)

8. Neuron-Derived Extracellular Vesicles: Emerging Biomarkers and Functional Mediators in Alzheimer's Disease, With Comparative Insights Into Neurodevelopment and Aging

Gonul C. P., Karacicek B., GENÇ Ş.

Developmental Neurobiology , cilt.85, sa.3, 2025 (SCI-Expanded, Scopus)

9. The Role of tRNA Fragments on Neurogenesis Alteration by H₂O₂-induced Oxidative Stress

Karacicek B., Katkat E., Binokay L., Ozhan G., KARAKÜLAH G., GENÇ Ş.

Journal of Molecular Neuroscience , cilt.75, sa.2, 2025 (SCI-Expanded, Scopus)

10. Microglia-like cells from patient monocytes demonstrate increased phagocytic activity in probable Alzheimer's disease

Gonul C. P., Kiser C., YAKA E., ÖZ D., Hunerli D., Yerlikaya D., et al.

Molecular and Cellular Neuroscience , cilt.132, 2025 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

11. The Impact of Neuroinflammation on Neuronal Damage in the Neonatal Rodents Brain

GENÇ Ş.

ACTA PHYSIOLOGICA , cilt.241, ss.13, 2025 (SCI-Expanded, Scopus)

12. The Impact of Neuroinflammation on Neuronal Damage in the Neonatal Rodents Brain

GENÇ Ş.

ACTA PHYSIOLOGICA , cilt.241, 2025 (SCI-Expanded, Scopus)

13. The Impact of Neuroinflammation on Neuronal Damage in the Neonatal Rodents Brain

GENÇ Ş.

ACTA PHYSIOLOGICA , cilt.241, 2025 (SCI-Expanded, Scopus)

14. The Impact of Neuroinflammation on Neuronal Damage in the Neonatal Rodents Brain

GENÇ Ş.

ACTA PHYSIOLOGICA , cilt.241, 2025 (SCI-Expanded, Scopus)

15. Supplemental oxygen alters the pentose phosphate pathway in the developing mouse brain through SIRT signaling

Engur D., CİLAKER MIÇILI S., Soy S., Bilici G., Tufekci K. U., Kiser C., et al.

Neurochemistry International , cilt.180, 2024 (SCI-Expanded, Scopus)

16. Biomarkers of NRF2 signalling: Current status and future challenges

Morgenstern C., Lastres-Becker I., Demirdöğen B. C., Costa V. M., Daiber A., Foresti R., et al.

Redox Biology , cilt.72, 2024 (SCI-Expanded, Scopus)

17. Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia

Kiser C., Gonul C. P., GENÇ Ş.

Cytotechnology , cilt.76, sa.2, ss.197-208, 2024 (SCI-Expanded, Scopus)

18. Proximity extension assay-based proteomics studies in neurodegenerative disorders and multiple sclerosis

Arioz B. I., Cotuk A., Yaka C. E., GENÇ Ş.

European Journal of Neuroscience , cilt.59, sa.6, ss.1348-1358, 2024 (SCI-Expanded, Scopus)

19. Ultrastructure of Digestive Canal of Aelia rostrata (Heteroptera: Pentatomidae)

GENÇ Ş., CANDAN S.

KSU TARIM VE DOGA DERGISI-KSU JOURNAL OF AGRICULTURE AND NATURE , cilt.27, sa.4, ss.881-891, 2024 (ESCI, TRDizin) Sürdürülebilir Kalkınma

20. Proximity extension assay-based proteomic studies in Alzheimer’s disease

Yaka E. C., GENÇ Ş.

Turk Noroloji Dergisi , cilt.30, sa.2, ss.69-75, 2024 (ESCI, Scopus, TRDizin)

21. Mitochondrial DNA oxidation, methylation, and copy number alterations in major and bipolar depression

Ceylan D., Karacicek B., Tufekci K. U., Aksahin I. C., Senol S. H., GENÇ Ş.

FRONTIERS IN PSYCHIATRY , cilt.14, 2023 (SCI-Expanded, SSCI, Scopus) Sürdürülebilir Kalkınma

22. New Perspective on the Pathogenesis of Infantile Colic: Is Infantile Colic a Biorhythm Disorder?

Ucuncu Egeli T., Tufekci K. U., Ural C., Durur D. Y., Erdogan F., Cavdar Z., et al.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION , cilt.77, sa.2, ss.171-177, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

23. Bilirubin induces microglial NLRP3 inflammasome activation in vitro and in vivo

Ercan I., CİLAKER MIÇILI S., Soy S., Engur D., Tufekci K. U., Kumral A., et al.

Molecular and Cellular Neuroscience , cilt.125, 2023 (SCI-Expanded, Scopus)

24. **Hydrogen peroxide signaling modulates neuronal differentiation via microglial polarization and Wnt/β- catenin pathway**

Engur D., Ercan I., Kiser C., Tufekci K. U., Soy S., Micili S., et al.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES , cilt.27, sa.11, ss.5083-5096, 2023 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

25. In vitro effects of H2O2 on neural stem cell differentiation

Eltutan B. I., Kiser C., Ercan I., Tufekci K. U., Engur D., GENÇ Ş., et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL , cilt.58, sa.9, ss.810-816, 2022 (SCI-Expanded, Scopus)

26. Melatonin Alters the miRNA Transcriptome of Inflammasome Activation in Murine Microglial Cells

Tarakcioglu E., Tastan B., Arioz B., Tufekci K. U., Genc S.

NEUROCHEMICAL RESEARCH , cilt.47, sa.10, ss.3202-3211, 2022 (SCI-Expanded, Scopus)

27. Pros and cons of NRF2 activation as adjunctive therapy in rheumatoid arthritis.

Manda G., Milanesi E., Genc Ş., Niculite C. M., Neagoe I. V., Tastan B., et al.

Free radical biology & medicine , cilt.190, ss.179-201, 2022 (SCI-Expanded, Scopus)

28. Alteration of miRNAs in Small Neuron-Derived Extracellular Vesicles of Alzheimer's Disease Patients and the Effect of Extracellular Vesicles on Microglial Immune Responses

Durur D. Y., Tastan B., Tufekci K. U., Olcum M., Uzuner H., Karakulah G., et al.

JOURNAL OF MOLECULAR NEUROSCIENCE , cilt.72, sa.6, ss.1182-1194, 2022 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

29. Targeting NLRP3 Inflammasome With Nrf2 Inducers in Central Nervous System Disorders.

Tastan B., Arioz B. I., Genc Ş.

Frontiers in immunology , cilt.13, ss.865772, 2022 (SCI-Expanded, Scopus)

30. Resveratrol Inhibits NLRP3 Inflammasome-Induced Pyroptosis and miR-155 Expression in Microglia Through Sirt1/AMPK Pathway

Tufekci K. U., Eltutan B. I., Isci K. B., Genc Ş.

NEUROTOXICITY RESEARCH , cilt.39, sa.6, ss.1812-1829, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

31. Inhibitory effects of sulforaphane on NLRP3 inflammasome activation

Kiser C., Gonul C. P., Olcum M., GENÇ Ş.

MOLECULAR IMMUNOLOGY , cilt.140, ss.175-185, 2021 (SCI-Expanded, Scopus)

32. Dimethyl Fumarate Alleviates NLRP3 Inflammasome Activation in Microglia and Sickness Behavior in LPS-Challenged Mice

Tastan B., Arioz B. I., Tufekci K. U., Tarakcioglu E., Gonul C. P., Genc K., et al.

FRONTIERS IN IMMUNOLOGY , cilt.12, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

33. **Induced microglia from mononuclear cells as in vitro platforms to study inflammatory responses in Alzheimer's patients**

Gonul C. P., Kiser C., Oz D., Gunduz D. H., Yerlikaya D., Yener G., et al.

GLIA , cilt.69, 2021 (SCI-Expanded, Scopus)

34. The Role of Melatonin on NLRP3 Inflammasome Activation in Diseases

Arioz B. I., Tarakcioglu E., Olcum M., GENÇ Ş.

ANTIOXIDANTS , cilt.10, sa.7, 2021 (SCI-Expanded, Scopus)

35. Antiviral microRNA expression signatures are altered in subacute sclerosing panencephalitis

Tufekci K. U., Allmer J., Carman K. B., BAYRAM E., TOPÇU Y., Hiz S., et al.

NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY , cilt.38, sa.3, ss.166-172, 2021 (SCI-Expanded, Scopus, TRDizin) Sürdürülebilir Kalkınma

36. In vivo and in vitro effects of bilirubin on NLRP3 inflammasome activation

Ercan I., Micili S., Engur D., Baysal B., Kumral A., Genc Ş.

GLIA , cilt.69, 2021 (SCI-Expanded, Scopus)

37. Proteome profiling of neuron-derived exosomes in Alzheimer's disease reveals hemoglobin as a potential biomarker

Arioz B. I., Tufekci K. U., Olcum M., Durur D. Y., Akarlar B. A., Ozlu N., et al.

NEUROSCIENCE LETTERS , cilt.755, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

38. Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling

Olcum M., Tufekci K. U., Durur D. Y., Tastan B., Gokbayrak I. N., Genc K., et al.

ANTIOXIDANTS , cilt.10, sa.5, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

39. Sulforaphane inhibits NLRP3 inflammasome activation in microglia through Nrf2-mediated miRNA alteration

Tufekci K. U., Ercan I., Isci K. B., Olcum M., Tastan B., Gonul C. P., et al.

IMMUNOLOGY LETTERS , cilt.233, ss.20-30, 2021 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

40. Lithium inhibits oxidative stress-induced neuronal senescence through miR-34a

Tufekci K. U., Alural B., Tarakcioglu E., San T., Genc Ş.

MOLECULAR BIOLOGY REPORTS , cilt.48, sa.5, ss.4171-4180, 2021 (SCI-Expanded, Scopus)

41. ENDOTHELIAL PROTEIN C RECEPTOR EXPRESSION IS REGULATED BY SP1 TRANSCRIPTION FACTOR IN MURINE MICROGLIA

Tüfekci K. U., Ateş H., Genç Ş.

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES , cilt.5, sa.1, ss.6-13, 2021 (ESCI)

42. Oxygen exposure in early life activates NLRP3 inflammasome in mouse brain

CİLAKER MIÇILI S., Engur D., GENÇ Ş., Ercan I., Soy S., Baysal B., et al.

NEUROSCIENCE LETTERS , cilt.738, 2020 (SCI-Expanded, Scopus)

43. Inhibitory effects of phytochemicals on NLRP3 inflammasome activation: A review

Olcum M., Tastan B., Ercan I., Eltutan I. B., GENÇ Ş.

PHYTOMEDICINE , cilt.75, 2020 (SCI-Expanded, Scopus)

44. Circulating exosomal microRNAs in bipolar disorder

Ceylan D., Tufekci K. U., Keskinoğlu P., Genç Ş., Ozerdem A.

JOURNAL OF AFFECTIVE DISORDERS , cilt.262, ss.99-107, 2020 (SCI-Expanded, SSCI, Scopus) Sürdürülebilir Kalkınma

45. Microglial NLRP3 inflammasome activation in multiple sclerosis.

Olcum M., Tastan B., Kiser C., Genc Ş., Genc K.

Advances in protein chemistry and structural biology , cilt.119, ss.247-308, 2020 (SCI-Expanded, Scopus)

46. Examination of IL-1 beta level as an inflammasome marker in Alzheimer's disease

Bulut O., Tanburoglu A., Boluk G., Demir N., Eren E., Vurgun U., et al.

NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY , cilt.36, sa.3, ss.141-147, 2019 (SCI-Expanded, Scopus, TRDizin)

47. Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway

Arioz B., Tastan B., Tarakcioglu E., Tufekci K. U., Olcum M., Ersoy N., et al.

FRONTIERS IN IMMUNOLOGY , cilt.10, 2019 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

48. Stem Cell Therapy for Multiple Sclerosis

Genc B., Bozan H. R., GENÇ Ş., Genc K.

TISSUE ENGINEERING AND REGENERATIVE MEDICINE , cilt.1084, ss.145-174, 2019 (SCI-Expanded)

49. Follow-up Analysis of Serum TNF-Related Apoptosis-Inducing Ligand Protein and mRNA Expression in Peripheral Blood Mononuclear Cells from Patients with Ischemic Stroke

Tufekci K. U., Vurgun U., Yigitaslan O., Keskinoğlu P., Yaka E., Kutluk M. K., et al.

FRONTIERS IN NEUROLOGY , cilt.9, 2018 (SCI-Expanded, Scopus)

50. Peptide Derivatives of Erythropoietin in the Treatment of Neuroinflammation and Neurodegeneration

Ercan I., Tufekci K. U., Karaca E., GENÇ Ş., Genc K.

THERAPEUTIC PROTEINS AND PEPTIDES , cilt.112, ss.309-357, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

51. Sulforaphane Inhibits Lipopolysaccharide-Induced Inflammation, Cytotoxicity, Oxidative Stress, and miR-155 Expression and Switches to Mox Phenotype through Activating Extracellular Signal-Regulated Kinase 1/2-Nuclear Factor Erythroid 2-Related Factor 2/Antioxidant Response Element Pathway in Murine Microglial Cells

Eren E., Tufekci K. U., Isci K. B., Tastan B., Genc K., GENÇ Ş.

FRONTIERS IN IMMUNOLOGY , cilt.9, 2018 (SCI-Expanded, Scopus)

52. Proteomic analysis of erythropoietin-induced changes in neuron-like SH-SY5Y cells

Erbayraktar Z., Onkal Z., Genc K. K., GENÇ Ş.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.42, sa.2, ss.213-221, 2017 (SCI-Expanded, Scopus, TRDizin)

53. MicroRNA exocytosis by large dense-core vesicle fusion

Gumurdu A., Yildiz R., Eren E., KARAKÜLAH G., Unver T., GENÇ Ş., et al.

SCIENTIFIC REPORTS , cilt.7, 2017 (SCI-Expanded, Scopus)

54. Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: Past, present, and future

Alural B., GENÇ Ş., Haggarty S. J.

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY , cilt.73, ss.87-103, 2017 (SCI-Expanded, Scopus)

55. Erythropoietin Promotes Glioblastoma via miR-451 Suppression

Alural B., Ayyildiz Z. O., Tufekci K. U., GENÇ Ş., Genc K.

ERYTHROPOIETIN , cilt.105, ss.249-271, 2017 (SCI-Expanded) Sürdürülebilir Kalkınma

56. Stem Cell-Based Approaches for Treatment of Glioblastoma

Erkan E. P., Eren E., GENÇ Ş., Genc K. K.

NEUROLOGICAL REGENERATION , ss.65-82, 2017 (SCI-Expanded)

57. Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

van Doorn L. J. C. v. W., Gispert J. D., Kuiperij H. B., Claassen J. A. H. R., Arighi A., Baldeiras I., et al.

JOURNAL OF ALZHEIMERS DISEASE , cilt.56, sa.2, ss.543-555, 2017 (SCI-Expanded, Scopus)

58. Sulforaphane produces anti inflammatory effects by inhibiting NLRR3 inflammasome activation in microglial cells

İşci K. B., Alural B., TÜFEKCİ K. U., GENÇ Ş.

Anatomy , cilt.10, sa.Suppl 1, ss.1-85, 2016 (TRDizin)

59. Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

Kruse N., Persson S., Alcolea D., Bahl J. M. C., Baldeiras I., Capello E., et al.

NEUROBIOLOGY OF AGING , cilt.36, sa.9, ss.2587-2596, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

60. A practical guide to immunoassay method validation

Andreasson U., Perret-Liaudet A., van Doorn L. J. C. v. W., Blennow K., Chiasserini D., Engelborghs S., et al.

FRONTIERS IN NEUROLOGY , cilt.6, 2015 (SCI-Expanded, Scopus)

61. Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells

Alural B., Ozerdem A., Allmer J., Genc K., GENÇ Ş.

Frontiers in Cellular Neuroscience , cilt.9, 2015 (SCI-Expanded, Scopus)

62. Does Caffeine Consumption Modify Cerebrospinal Fluid Amyloid-beta Levels in Patients with Alzheimer's Disease?

Travassos M., Santana I., Baldeiras I., Tsolaki M., Gkatzima O., GENÇ Ş., et al.

JOURNAL OF ALZHEIMERS DISEASE , cilt.47, sa.4, ss.1069-1078, 2015 (SCI-Expanded, Scopus)

63. Expression Patterns of Micro-RNAs 146a, 181a, and 155 in Subacute Sclerosing Panencephalitis

YİŞ U., Tufekci U. K., GENÇ Ş., ÇARMAN K. B., Bayram E., Topcu Y., et al.

JOURNAL OF CHILD NEUROLOGY , cilt.30, sa.1, ss.69-74, 2015 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

64. EPO mediates neurotrophic, neuroprotective, anti-oxidant and anti-apoptotic effects via downregulation of miR-451 and miR-885-5p in SH-SY5Y neuron-like cells

Alural B., Duran G. A., Tufekci K. U., Allmer J., Onkal Z., Tunali D., et al.

FRONTIERS IN IMMUNOLOGY , cilt.5, 2014 (SCI-Expanded, Scopus)

65. The Role of MicroRNAs in Human Diseases

Tufekci K. U., Oner M. G., Meuwissen R. L. J., GENÇ Ş.

MIRNOMICS: MICRORNA BIOLOGY AND COMPUTATIONAL ANALYSIS , cilt.1107, ss.33-50, 2014 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

66. The Role of MicroRNAs in Biological Processes

Tufekci K. U., Meuwissen R. L. J., GENÇ Ş.

MIRNOMICS: MICRORNA BIOLOGY AND COMPUTATIONAL ANALYSIS , cilt.1107, ss.15-31, 2014 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

67. Neurodegenerative Disease Phenotypes in Carriers of MAPT p.A152T, A Risk Factor for Frontotemporal Dementia Spectrum Disorders and Alzheimer Disease

Lee S. E., Tartaglia M. C., Yener G., GENÇ Ş., Seeley W. W., Sanchez-Juan P., et al.

ALZHEIMER DISEASE & ASSOCIATED DISORDERS , cilt.27, sa.4, ss.302-309, 2013 (SCI-Expanded, Scopus)

68. ASSOCIATION OF PERIPHERAL VISFATIN LEVELS AND VISFATIN G-948T GENE POLYMORPHISM WITH ALZHEIMER'S DISEASE IN A TURKISH POPULATION

Vurgun U., Sahin O., Tufekci K. U., Keskinoğlu P., Yener G., Genc K. K., et al.

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI , cilt.16, sa.2, ss.123-128, 2013 (SCI-Expanded, SSCI, Scopus, TRDizin) Sürdürülebilir Kalkınma

69. Resveratrol Reduces Matrix Metalloproteinase-2 Activity Induced by Oxygen-Glucose Deprivation and Reoxygenation in Human Cerebral Microvascular Endothelial Cells

ÇAVDAR Z., YÜKSEL EĞRİLMEZ M., ALTUN Z. S., ARSLAN N., YENER N., SAYIN O., et al.

INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH , cilt.82, sa.4, ss.267-274, 2012 (SCI-Expanded, Scopus)

70. The adverse effects of air pollution on the nervous system

GENÇ Ş., Zadeoglulari Z., Fuss S. H., Genc K.

Journal of Toxicology , cilt.2012, 2012 (Scopus)

71. Inflammation in Parkinson's Disease

Tufekci K. U., Meuwissen R., GENÇ Ş., Genc K.

INFLAMMATION IN NEUROPSYCHIATRIC DISORDERS , cilt.88, ss.69-132, 2012 (SCI-Expanded) Sürdürülebilir Kalkınma

72. MicroRNAs and multiple sclerosis

Tufekci K. U., Oner M. G., GENÇ Ş., Genc K.

Autoimmune Diseases , cilt.1, sa.1, 2011 (Scopus)

73. The Diagnostic Role of Dual Phase F-18 FDG PET/CT in Characterization of Solitary Pulmonary Nodules

Demir Y., Polack B. D., Genc Ş., Karaman C., Gurel D., Ayhan S., et al.

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , cilt.38, 2011 (SCI-Expanded, Scopus)

74. Erythropoietin in neonatal brain protection: the past, the present and the future.

KUMRAL A., Tuzun F., Oner M. G., GENÇ Ş., Duman N., ÖZKAN H.

Brain & development , cilt.33, sa.8, ss.632-43, 2011 (SCI-Expanded, Scopus)

75. Intranasal erythropoietin therapy in nervous system disorders

GENÇ Ş., Zadeoglulari Z., Oner M. G., Genc K., Digicaylioglu M.

EXPERT OPINION ON DRUG DELIVERY , cilt.8, sa.1, ss.19-32, 2011 (SCI-Expanded, Scopus)

76. The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease

Tufekci K. U., Bayin E. C., GENÇ Ş., Genc K.

PARKINSONS DISEASE , cilt.2011, 2011 (SCI-Expanded, Scopus)

77. Patient-Specific Pluripotent Stem Cells in Neurological Diseases

Durnaoglu S., GENÇ Ş., Genc K.

STEM CELLS INTERNATIONAL , cilt.2011, 2011 (SCI-Expanded, Scopus)

78. The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease

Tufekci K. U., GENÇ Ş., Genc K.

PARKINSONS DISEASE , cilt.2011, 2011 (SCI-Expanded, Scopus)

79. White Matter Protection by Erythropoietin: An Emerging Matter in the Treatment of Neonatal Hypoxic-Ischemic Brain Injury

GENÇ Ş., Genc K., KUMRAL A., ÖZKAN H.

STROKE , cilt.41, sa.11, 2010 (SCI-Expanded, Scopus)

80. Cerebrospinal fluid and serum βeta secretase activities in Alzheimer's disease

Yaka E., Genc S., İyilikçi L., Yener G. G.

Journal of Neurological Sciences (Turkish) , cilt.27, sa.1, ss.69-74, 2010 (SCI-Expanded, TRDizin)

81. Safety Concerns With the Clinical Use of Erythropoietin in Acute Ischemic Stroke

KUMRAL A., GENÇ Ş., KUTLUK M. K., ÖZKAN H.

STROKE , cilt.41, sa.7, 2010 (SCI-Expanded, Scopus)

82. Erythropoietin induces nuclear translocation of Nrf2 and heme oxygenase-1 expression in SH-SY5Y cells

Genc K., Yüksel Eğrilmez M., Genç Ş.

CELL BIOCHEMISTRY AND FUNCTION , cilt.28, sa.3, ss.197-201, 2010 (SCI-Expanded, Scopus)

83. In vitro reoxygenation following hypoxia increases MMP-2 and TIMP-2 secretion by human umbilical vein endothelial cells

Çavdar Z., Oktay G., Yüksel Eğrilmez M., Genç Ş., Genc K., Altun Z. S., et al.

ACTA BIOCHIMICA POLONICA , cilt.57, sa.1, ss.69-73, 2010 (SCI-Expanded, Scopus)

84. Development of an in vitro Injury Model of Ischemia Reperfusion in Human Brain Microvascular Endothelial Cells and the Evaluation of Cell Injury

ARSLAN N., SAYIN O., ALTUN Z. S., ÇAVDAR Z., YÜKSEL EĞRİLMEZ M., YENER N., et al.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.35, sa.3, ss.195-202, 2010 (SCI-Expanded, Scopus, TRDizin)

85. THERAPEUTIC EFFECT OF ERYTHROPOIETIN IN AN EXPERIMENTAL IN VIVO ALZHEIMER'S DISEASE ANIMAL MODEL MODERATED BY D-GALACTOSE INJECTION AT OVARIECTOMIZED RATS

Sahim O., Vurgun U., Yılmaz O., Sönmez A., Dayı A., Yener G., et al.

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI , cilt.13, sa.3, ss.145-149, 2010 (SCI-Expanded)

86. Protective Effects of Methylxanthines on Hypoxia-Induced Apoptotic Neurodegeneration and Long-Term Cognitive Functions in the Developing Rat Brain

KUMRAL A., Yesilirmak D. C., Aykan S., GENÇ Ş., TUĞYAN K., CİLAKER MIÇILI S., et al.

NEONATOLOGY , cilt.98, sa.2, ss.128-136, 2010 (SCI-Expanded, Scopus)

87. Cerebrospinal Fluid and Serum Beta Secretase Activities in Alzheimer's Disease

YAKA E., GENÇ Ş., İYİLİKÇİ KARAOĞLAN L., Yener G.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH , cilt.27, sa.1, ss.69-74, 2010 (SCI-Expanded, Scopus, TRDizin)

88. How Does Early and Late Reoxygenation Following Hypoxia Affect Human Umbilical Vascular Endothelial Cells in Respect to Oxidative Stress?

ALTUN Z. S., İŞLEKEL G. H., SAYIN O., YÜKSEL EĞRİLMEZ M., GENÇ Ş., Genc K., et al.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI , cilt.35, sa.3, ss.225-229, 2010 (SCI-Expanded, Scopus, TRDizin)

89. **Biological markers in cerebrospinal fluid (CSF) and evaluation of in vitro effect of CSF on PC12 cell line viability in Alzheimer's disease**

YAKA E., YÜKSEL EĞRİLMEZ M., Keskinoglu P., ÇAVDAR Z., GENÇ Ş., Genc K., et al.

CELL BIOCHEMISTRY AND FUNCTION , cilt.27, sa.6, ss.395-401, 2009 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

90. TNF-related apoptosis-inducing ligand level in Alzheimer's disease

GENÇ Ş., YÜKSEL EĞRİLMEZ M., YAKA E., ÇAVDAR Z., İYİLİKÇİ KARAOĞLAN L., Yener G., et al.

NEUROLOGICAL SCIENCES , cilt.30, sa.3, ss.263-267, 2009 (SCI-Expanded, Scopus)

91. Protective Effects of Topiramate against Hyperoxic Brain Injury in the Developing Brain

Kurul S. H., Yis U., Kumral A., Tugyan K., Cilaker S., KOLATAN H. E., et al.

NEUROPEDIATRICS , cilt.40, sa.1, ss.22-27, 2009 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

92. Oxidative stress and dysregulated Nrf2 activation in the pathogenesis of schizophrenia

Genc K., GENÇ Ş.

Bioscience Hypotheses , cilt.2, sa.1, ss.16-18, 2009 (Scopus)

93. Pregnenolone protects the PC-12 cell line against amyloid beta peptide toxicity but its sulfate ester does not

Akan P., Kızıldağ S., Örmen M., Genç Ş., Oektem M. A., Fadiloglu M.

CHEMICO-BIOLOGICAL INTERACTIONS , cilt.177, sa.1, ss.65-70, 2009 (SCI-Expanded, Scopus)

94. The Effect of Erythropoietin on Neurotrophic Factors in N9 Murine Microglial Cells

Kuralay F., Cakirli B. B., GENÇ Ş.

TURKISH JOURNAL OF MEDICAL SCIENCES , cilt.38, sa.6, ss.519-524, 2008 (SCI-Expanded, Scopus, TRDizin)

95. Effect of erythropoietin on oxygen-induced brain injury in the newborn rat

YİŞ U., Kurul S. H., KUMRAL A., TUĞYAN K., CİLAKER MIÇILI S., YILMAZ O., et al.

NEUROSCIENCE LETTERS , cilt.448, sa.3, ss.245-249, 2008 (SCI-Expanded, Scopus)

96. Hyperoxic exposure leads to cell death in the developing brain

YİŞ U., Kurul S. H., KUMRAL A., CİLAKER MIÇILI S., TUĞYAN K., GENÇ Ş., et al.

BRAIN & DEVELOPMENT , cilt.30, sa.9, ss.556-562, 2008 (SCI-Expanded, Scopus)

97. Oxidative DNA damage in polymorphonuclear leukocytes of patients with familial Mediterranean fever

Kirkali G., Tunca M., GENÇ Ş., Jaruga P., Dizdaroglu M.

FREE RADICAL BIOLOGY AND MEDICINE , cilt.44, sa.3, ss.386-393, 2008 (SCI-Expanded, Scopus)

98. Activated protein C reduces endotoxin-induced white matter injury in the developing rat brain

Yesilirmak D. C., Kumral A., Baskın A. H., Ergur B. U., Aykan S., Genç Ş., et al.

BRAIN RESEARCH , cilt.1164, ss.14-23, 2007 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

99. (99)'Tc-HMPAO labelling inhibits cell motility and cell proliferation and induces apoptosis of NC-NC cells

Ulker O., Genç Ş., Ateş H., Durak H., Atabey N.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS , cilt.631, sa.2, ss.69-76, 2007 (SCI-Expanded, Scopus)

100. Erythropoietin attenuates lipopolysaccharide-induced white matter injury in the neonatal rat brain

Kumral A., BASKIN A. H., Yesilirmak D. C., Ergur B. U., Aykan S., GENÇ Ş., et al.

NEONATOLOGY , cilt.92, sa.4, ss.269-278, 2007 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

101. Neuroprotective effect of the peptides ADNF-9 and NAP on hypoxic-ischemic brain injury in neonatal rats

Kumral A., Yesilirmak D. C., Sonmez Ü., BASKIN A. H., Tugyan K., Yilmaz O., et al.

BRAIN RESEARCH , cilt.1115, ss.169-178, 2006 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

102. Erythropoietin decreases apoptosis induced by 6-hydroxydopamine in PC12 cells

Genç Ş., Ay M. E., Ateş H.

Turk Geriatri Dergisi , cilt.9, sa.1, ss.13-18, 2006 (SCI-Expanded, Scopus, TRDizin)

103. Biochemical markers in cerebrospinal fluid (CSF) and evaluation of the effect of CSF on PC12 cell line viability in Alzheimer's disease Alzhei̇mer hastaliǧinda beyi̇n omuri̇li̇k sivisinda (BOS) bi̇yoloji̇k beli̇rteçler ve bos'un PC12 hücre hatti canliligǐ üzeri̇ne i̇n vi̇tro etki̇si̇Eni̇n deǧerlendi̇ri̇lmesi̇

YAKA E., YÜKSEL EĞRİLMEZ M., KESKİNOĞLU P., ÇAVDAR Z., GENÇ Ş., Genç K., et al.

Turk Geriatri Dergisi , cilt.9, sa.1, ss.1-7, 2006 (Scopus, TRDizin)

104. Alzheimer Hastalığında Beyin Omurilik Sıvısında (BOS) Biyolijik Belirteçler ve BOS'un PC12 Hücre Hattı Canlılığı Üzerine in Vitro Etkisinin Değerlendirilmesi

Yaka E., Yüksel Eğrilmez M., Keskinoğlu P., Çavdar Z., Genç Ş., İyilikçi Karaoğlan L., et al.

TURK GERIATRI DERGISI , cilt.9, sa.1, ss.9, 2006 (Scopus, TRDizin)

105. Alzheimer hastalığında beyin omurilik sıvısında (BOS) biyolojik belirteçler ve BOS'un PC12 hücre hattı canlılığı üzerine in vitro etkisinin değerlendirilmesi

Yaka E., EĞRİLMEZ Y. M., KESKİNOĞLU P., Cavdar Z., Genc S., GENÇ K. K., et al.

Türk Geriatri Dergisi , cilt.9, sa.1, ss.1-7, 2006 (Scopus, TRDizin)

106. Erythropoietin signaling and neuroprotection

Genç Ş., Yuksel Egrilmez M., Genc K.

CURRENT SIGNAL TRANSDUCTION THERAPY , cilt.1, sa.2, ss.209-218, 2006 (SCI-Expanded, Scopus)

107. Erythropoietin downregulates Bax and DP5 ProApoptotic gene expression in neonatal hypoxic-ischemic brain injury

Kumral A., Genc Ş., Ozer E., Yilmaz O., Gokmen N., Koroglu T., et al.

BIOLOGY OF THE NEONATE , cilt.89, sa.3, ss.205-210, 2006 (SCI-Expanded) Sürdürülebilir Kalkınma

108. Erythropoietin decreases cytotoxicity and nitric oxide formation induced by inflammatory stimuli in rat oligodendrocytes

Genc K., Genc Ş., BASKIN A. H., Semin I.

PHYSIOLOGICAL RESEARCH , cilt.55, sa.1, ss.33-38, 2006 (SCI-Expanded, Scopus)

109. Endothelial nitric oxide-mediated Nrf2 activation as a novel mechanism for vascular and neuroprotection by erythropoietin in experimental subarachnoid hemorrhage.

Genc Ş., Egrilmez M., Genc K.

Medical hypotheses , cilt.67, sa.2, ss.424, 2006 (SCI-Expanded, Scopus)

110. Protective effects of erythropoietin against ethanol-induced apoptotic neurodegenaration and oxidative stress in the developing C57BL/6 mouse brain

Kumral A., Tugyan K., Gonenc S., Genc K., Genc Ş., Sonmez Ü., et al.

DEVELOPMENTAL BRAIN RESEARCH , cilt.160, sa.2, ss.146-156, 2005 (SCI-Expanded) Sürdürülebilir Kalkınma

111. Biochemical markers in cerebrospinal fluid (CSF) and evaluation of the effect of CSF on PC 12 cell line viability in Alzheimer's disease

Yaka E., Genc Ş., Genc K., ÇAVDAR Z., Egrilmez M. Y., İYİLİKÇİ KARAOĞLAN L., et al.

EUROPEAN JOURNAL OF NEUROLOGY , cilt.12, ss.194, 2005 (SCI-Expanded, Scopus)

112. Does antioxidant supplementation alter the effects of acute exercise on erythrocyte aggregation, deformability and endothelium adhesion in untrained rats?

Kayatekin B. M., UYSAL HARZADIN N., Resmi H., BEDİZ C. Ş., Temiz-Artmann A., GENÇ Ş., et al.

INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH , cilt.75, sa.4, ss.243-250, 2005 (SCI-Expanded, Scopus)

113. Hyperbilirubinemic serum is cytotoxic and induces apoptosis in murine astrocytes

Kumral A., Genc Ş., Genc K., Duman N., Tatli M., Sakizli M., et al.

BIOLOGY OF THE NEONATE , cilt.87, sa.2, ss.99-104, 2005 (SCI-Expanded) Sürdürülebilir Kalkınma

114. RNA interference in neuroscience

Genc Ş., Koroglu T., Genc K.

MOLECULAR BRAIN RESEARCH , cilt.132, sa.2, ss.260-270, 2004 (SCI-Expanded, Scopus)

115. Erythropoietin improves long-term spatial memory deficits and brain injury following neonatal hypoxia-ischemia in rats

Kumral A., UYSAL HARZADIN N., Tugyan K., Sonmez A., Yilmaz O., Gokmen N., et al.

BEHAVIOURAL BRAIN RESEARCH , cilt.153, sa.1, ss.77-86, 2004 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

116. Analysis of cytotoxic T lymphocyte antigen-4 (CTLA-4) exon 1 polymorphism in patients with type 1 diabetes mellitus in a Turkish population

Genc Ş., Genc K., Sercan O., Kizildag S., Gulay Z., Atay T., et al.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM , cilt.17, sa.5, ss.731-735, 2004 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

117. Erythropoietin and the nervous system

Genc Ş., Koroglu T., Genc K.

BRAIN RESEARCH , cilt.1000, ss.19-31, 2004 (SCI-Expanded, Scopus)

118. Selective inhibition of nitric oxide in hypoxic-ischemic brain model in newborn rats: Is it an explanation for the protective role of erythropoietin?

Kumral A., BASKIN A. H., Gokmen N., Yilmaz O., Genc K., Genc Ş., et al.

BIOLOGY OF THE NEONATE , cilt.85, sa.1, ss.51-54, 2004 (SCI-Expanded) Sürdürülebilir Kalkınma

119. Diabetik hasta serumunun sıçanda Schwann hücre canlılığı üzerine in vitro etkisi

Özyurt D., Genç K. K., Genç Ş., Tekmen I., Sönmez Ü., Altungöz O., et al.

Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi , cilt.18, sa.3, ss.221-227, 2004 (TRDizin) Sürdürülebilir Kalkınma

120. Erythropoietin as a novel neuroprotectant

Genc Ş., Koroglu T., Genc K.

RESTORATIVE NEUROLOGY AND NEUROSCIENCE , cilt.22, sa.2, ss.105-119, 2004 (SCI-Expanded, Scopus)

121. Erythropoietin protects against necrotizing enterocolitis of newborn rats by the inhibiting nitric oxide formation

Kumral A., BASKIN A. H., Duman N., Yilmaz O., Tatli M., Ozer E., et al.

BIOLOGY OF THE NEONATE , cilt.84, sa.4, ss.325-329, 2003 (SCI-Expanded) Sürdürülebilir Kalkınma

122. Bilirubin is cytotoxic to rat oligodendrocytes in vitro

Genc Ş., Genc K., Kumral A., BASKIN A. H., ÖZKAN H.

BRAIN RESEARCH , cilt.985, sa.2, ss.135-141, 2003 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

123. Methamphetamine induces oligodendroglial cell death in vitro

Genc K., Genc Ş., Kizildag S., Sonmez Ü., Yilmaz O., Tugyan K., et al.

BRAIN RESEARCH , cilt.982, sa.1, ss.125-130, 2003 (SCI-Expanded, Scopus)

124. Interferon gamma and lipopolysaccharide upregulate TNF-related apoptosis-inducing ligand expression in murine microglia

Genc Ş., Kizyldag S., Genc K., Ateş H., Atabey N.

IMMUNOLOGY LETTERS , cilt.85, sa.3, ss.271-274, 2003 (SCI-Expanded, Scopus)

125. Neuroprotective effect of erythropoietin on hypoxic-ischemic brain injury in neonatal rats

Kumral A., Ozer E., Yilmaz O., Akhisaroglu M., Gokmen N., Duman N., et al.

BIOLOGY OF THE NEONATE , cilt.83, sa.3, ss.224-228, 2003 (SCI-Expanded) Sürdürülebilir Kalkınma

126. Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro

Genc Ş., Akhisaroglu M., Kuralay F., Genc K.

NEUROSCIENCE LETTERS , cilt.321, ss.73-76, 2002 (SCI-Expanded, Scopus)

127. Erythropoietin prevents motor neuron apoptosis and neurologic disability in experimental spinal cord ischemic injury.

Celik M., Gokmen N., Erbayraktar S., Akhisaroglu M., Konakc S., Ulukus C., et al.

Proceedings of the National Academy of Sciences of the United States of America , cilt.99, sa.4, ss.2258-63, 2002 (SCI-Expanded, Scopus)

128. Serodiagnosis of tuberculosis by enzyme immunoassay using A60 antigen

Yuce A., Yucesoy M., Genc Ş., SAYAN M., Ucan E. S.

CLINICAL MICROBIOLOGY AND INFECTION , cilt.7, sa.7, ss.372-376, 2001 (SCI-Expanded, Scopus) Sürdürülebilir Kalkınma

129. Erythropoietin exerts neuroprotection in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/BL mice via increasing nitric oxide production

Genc Ş., Kuralay F., Genc K., Akhisaroglu M., Fadiloglu S., Yorukoglu K., et al.

NEUROSCIENCE LETTERS , cilt.298, sa.2, ss.139-141, 2001 (SCI-Expanded, Scopus)

130. A case of Lafora's disease associated with cardiac arrhythmia

Oksel F., Tekgul H., GENÇ Ş., Ozyurek R., Akalm T., Tututuncuoglu S.

JOURNAL OF CHILD NEUROLOGY , cilt.14, sa.11, ss.745-746, 1999 (SCI-Expanded, Scopus)

131. Parkinson Hastalığında Depresyon

GENÇ Ş., KIVICIK B. B., ALPTEKİN K., YENER G., FADILOĞLU Ş.

Parkinson Hastalığı ve Hareket Bozuklukları Dergisi , cilt.1, sa.1, ss.8-11, 1998 (Hakemli Dergi)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 62

1. INTRANASAL COLOSTRUM-DERIVED EXOSOMES AS A NEURORESTORATIVE TREATMENT FOR PERIVENTRICULAR LEUKOMALACIA IN RATS

ERDOĞAN F., Türe Ş. B., ARMAĞAN C., Güdücü Y., TAŞTAN B., AKYILDIZ C., et al.

Best Practice in Neonatology, 1st joint UENPS and EFCNI congress, Ljubljana, Slovenya, 3 - 05 Temmuz 2024, (Özet Bildiri)

2. THERAPEUTIC POTENTIAL OF PHYSIOLOGICAL STARVATION: IMPACT OF NUTRITIONAL SUPPORT ON AUTOPHAGY AND INFLAMMASOME DYNAMICS IN AN LPS-INDUCED SEPSIS MODEL

BAKIR G., ARMAĞAN C., TÜFEKCİ K. U., ERDOĞAN F., GENÇ Ş., KESKİNOĞLU P., et al.

Best Practice in Neonatology, 1st joint UENPS and EFCNI congress, Ljubljana, Slovenya, 3 - 05 Temmuz 2024, (Özet Bildiri)

3. KOLOSTRUM KÖKENLİ İNTRANAZAL EKSOZOM TEDAVİSİNİN PVL SIÇAN MODELİNDE NÖRORESTORATİF ETKİNLİĞİNİN DEĞERLENDİRİLMESİ

ERDOĞAN F., Türe Ş. B., ARMAĞAN C., Taştan B., AKYILDIZ C., Güdücü Y., et al.

31. Ulusal Neonatoloji Kongresi, Antalya, Türkiye, 24 Nisan 2024, ss.19-20, (Özet Bildiri)

4. Alzheimer39;s disease (AD) is a neurodegenerative disorder clinically characterized by progressive memory loss and cognitive decline. Pathological hallmarks of the disease are the formation of amyloid plaques and neurofibrillary tangles. Several research has demonstrated that AD-related pathological changes occur long before clinical symptoms are manifested. Thus, it is crucial to establish an accurate diagnosis at an early stage, particularly for individuals aged 60 years and above. Biomarkers serve as vital tools for AD diagnosis, monitoring, early detection, therapeutic intervention, and preventing inaccurate diagnoses. Still, there are no robust tools or biomarkers that can provide precise information for the diagnosis of AD. tRNA-derived fragments (tRFs) are a distinctive type of small non-coding RNAs produced from tRNAs via nucleases Dicer and Angiogenin. tRFs can regulate biological functions such as translation and transcription. Recently, there has been much attention drawn to the previously unexplored connection between tRFs and neurodegenerative disorders. Extracellular vesicles (EVs) are vesicles with lipid membranes and contain numerous different molecules, such as nucleic acids, proteins, and lipids. Within their cargo contents, EVs contribute to development, cell growth, and survival, intercellular communication, and waste disposal, but also to disease pathogenesis. Just like all other cell types, neurons also secrete extracellular vesicles, and neuron-derived extracellular vesicles (NDEVs) may contain distinctive cargoes. In this study, we profiled the tRF content of neuron-derived extracellular vesicles (NDEVs) of AD patients and healthy controls (HCs) with next-generation sequencing. We demonstrated that six tRFs (ProAGG, GluTTC, LysCTT, LeuAAG, SerAGA, ValCAC) were differentially expressed in NDEVs of AD patients compared to HCs. Further, we confirmed those tRFs on a considerably larger population with the RT-qPCR method. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes annotation also indicated that these are enriched in various neuron and brain-related categories; for example, axogenesis (GO:0007409), regulation of nervous system development (GO:0051960), and regulation of neuron projection development (GO:0010975). Taken together, our results indicate that dysregulated tRFs have the potential to serve as a biomarker for AD in future investigations.

Genç Ş.

The 7th Venusberg Meeting on Neuroinflammation, Luxembourg, Lüksemburg, 11 - 13 Mayıs 2023, ss.1, (Özet Bildiri)

5. The effect of M1 and M2 polarized microglia-derived exosomes on neural stem cell differentiation

Genç Ş.

FENS Forum 2022 | International Neuroscience Conference, Paris, Fransa, 9 - 13 Temmuz 2022, ss.1, (Özet Bildiri)

6. NEAT1 regulates microglial NLRP3 inflammasome activation

Genç Ş.

8 International Congress of the Molecular Biology Association of Turkey, İstanbul, Türkiye, 9 - 12 Haziran 2022, ss.1, (Özet Bildiri) Sürdürülebilir Kalkınma

7. İNFANTİL KOLİK PATOGENEZİNE YENİ BİR BAKIŞ; İNFANTİL KOLİK BİR BİYORİTM DÜZENSİZLİĞİ MİDİR?

Üçüncü Egeli T., Erdoğan F., Ünal M. M., Tüfekci K. U., Ural Özkan C., Durur D., et al.

29. Ulusal Neonatoloji Kongresi, Antalya, Türkiye, 6 - 10 Ekim 2021, ss.1, (Özet Bildiri)

8. LncRNA NEAT1'in mikroglial NLRP3 inflamazom aktivasyonunda düzenleyici rolü

Genç Ş.

The inflammasomes: The next frontier, Munich, Almanya, 21 - 24 Eylül 2021, (Özet Bildiri)

9. Induced microglia from mononuclear cells as in vitro platforms to study inflammatory responses in Alzheimer's patients

Gönül C. P., Kiser Ç., ÖZ D., Hünerli Gündüz D., YENER G., GENÇ Ş.

XV. European Meeting on Glial Cells in Health and Disease, Marsilya, Fransa, 5 - 09 Temmuz 2021, ss.205-206, (Özet Bildiri)

10. PAR-2 AND PAR-4 RECEPTORS MEDIATE ANTI-INFLAMMATORY EFFECTS OF ACTIVATED PROTEIN C IN MICROGLIAL CELLS

TÜFEKCİ K. U., GENÇ Ş.

4th Health Sciences and Innovation Congress, Baku, Azerbaycan, 5 - 06 Temmuz 2021, ss.726-734, (Tam Metin Bildiri)

11. Hiperoksi beyin enerjisi metabolizmasında glikoliz yolağından pentoz fosfat yolağına yönelmeye neden olabilir mi?/Does hyperoxia cause a shift in brain energy metabolism from glycolysis to pentose phosphate pathway?

CİLAKER MIÇILI S., Engür D., TÜFEKCİ K. U., BAYSAL B., Eltutan B. İ., GENÇ Ş., et al.

6. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi (UTSAK), Ankara, Türkiye, 10 - 11 Nisan 2021, (Tam Metin Bildiri)

12. Investigation of the effect of melatonin on microRNA expression in the NLRP3 inflammasome model

Tarakçıoğlu E., TÜFEKCİ K. U., GENÇ Ş.

2nd International Medical Congress of Izmir Democracy University (IMCIDU 2020), İzmir, Türkiye, 17 - 19 Aralık 2020, (Tam Metin Bildiri)

13. Hiperoksi Beyin Enerjisi Metabolizmasında Glikoliz Yolağından Pentoz Fosfat Yolağına Yönelmeye Neden Olabilir Mi?

CİLAKER MIÇILI S., ENGÜR D., BAYSAL B., TÜFEKCİ K. U., ELTUTAN İ., GENÇ Ş., et al.

28. Ulusal Neonatoloji Kongresi, Türkiye, 10 Aralık 2020, (Özet Bildiri)

14. İn vitro redoks modulasyonunun nöral kök hücre farklılaşması üzerine etkileri

KUMRAL A., ELTUTAN İ., ENGÜR D., TÜFEKCİ K. U., ERCAN İ., CİLAKER MIÇILI S., et al.

28. Ulusal Neonatoloji Kongresi, Türkiye, 10 Aralık 2020, (Özet Bildiri)

15. The protective effect of erythropoietin on apoptotic cell death induced by amyloid beta in PC12 cells.

KIZILDAĞ S., GENÇ Ş., KURT S., KIZILDAĞ S., SAKIZLI M., FADILOĞLU M.

3rd International Eurasian Conference on Biological and Chemical Sciences, Ankara, Türkiye, 19 - 20 Mart 2020, ss.638-645, (Tam Metin Bildiri)

16. Circulating exosomal microRNAs in bipolar disorder

Ceylan D., Tufekci K. U., KESKİNOĞLU P., GENÇ Ş., Ozerdem A.

22nd Annual Conference of the International-Society-for-Bipolar-Disorders (ISBD), ELECTR NETWORK, 18 - 21 Haziran 2020, cilt.22, ss.55-56, (Özet Bildiri)

17. Alzheimer Hastalarının Nöron Derive Ekzozomlarının Proteomik Analizi

ARIÖZ B. İ., TÜFEKCİ K. U., Durur D. Y., OLÇUM UZAN M., ÖZLÜ N., YENER G., et al.

3. Ulusal Proteomik Kongresi, İstanbul, Türkiye, 27 - 29 Şubat 2020, ss.40, (Özet Bildiri)

18. ESTIMATION OF GENETIC VARIATION TYPES VIA MACHINE LEARNING

özgür s., COŞGUN E., TÜFEKCİ K. U., KESKİNOĞLU P., YENER G., GENÇ Ş., et al.

XXI. National and IV. International Biostatistics Congress, Antalya, Türkiye, 26 - 29 Ekim 2019, (Özet Bildiri)

19. Ekzozomal MikroRNA ların Santral Sinir Sistemindeki Yeri

GENÇ Ş.

16. Tıbbi Biyoloji ve Genetik Kongresi, Bodrum, Türkiye, 27 - 30 Ekim 2019, (Tam Metin Bildiri)

20. The impact of exosomes in brain disorders: from pathogenesis to clinical application

GENÇ Ş.

2. EBAT Congress, Antalya, Türkiye, 26 - 29 Ekim 2019, (Tam Metin Bildiri)

21. Microglial phenotypes are determined by variable intracellular hydrogen peroxide concentrations

TÜFEKCİ K. U., Ercan İ., Eltutan B. İ., GENÇ Ş.

XIV European Meeting on Glial Cells in Health and Disease, Portekiz, 10 - 13 Temmuz 2019, cilt.67, ss.1, (Özet Bildiri)

22. Microglial phenotypes are determined by variable intracellular hydrogen peroxide concentrations

Tufekci K. U., Ercan I., Eltutan B. I., Genc Ş.

14th European Meeting on Glial Cells in Health and Disease (GLIA), Porto, Portekiz, 10 - 13 Temmuz 2019, cilt.67, (Özet Bildiri)

23. Dimethyl Fumarate ameliorates NLRP3 inflammasome activation in murine microglia

Tastan B., Arioz B. I., Tufekci K. U., Genc Ş.

14th European Meeting on Glial Cells in Health and Disease (GLIA), Porto, Portekiz, 10 - 13 Temmuz 2019, cilt.67, (Özet Bildiri)

24. İnfantil Kolik Bir Biyoritim Bozukluğu mudur?

ÜÇÜNCÜ EGELİ T., TÜZÜN F., Durur D. Y., TÜFEKCİ K. U., URAL C., CENGİZ M. M., et al.

Ulusal Neonatoloji Kongresi (UNEKO 27), Antalya, Türkiye, 3 - 07 Nisan 2019, ss.14, (Özet Bildiri)

25. Exosomal microRNAs and microRNA dysregulation in bipolar disorder

Ceylan D., Tufekci U., GENÇ Ş., Ozerdem A.

21st Annual ISBD Conference on Global Advances in Bipolar Disorder and Depression, Sydney, Avustralya, 20 - 23 Mart 2019, cilt.21, ss.25, (Özet Bildiri)

26. Bilim ve Bilim Akademileri

GENÇ Ş.

6th International Congress of theMolecular Biology Associationof Turkey, 5 - 08 Eylül 2018, (Tam Metin Bildiri)

27. Nörodejenerasyonda inflamasyonun rolü

GENÇ Ş.

ULUSLARARASI KATILIMLI NÖRODEJENERASYON / NÖROREJENERASYON ÇALIŞTAYI, 4 - 05 Mayıs 2018, (Tam Metin Bildiri)

28. Altered expressions of exosomal micrornas in bipolar disorder

Ceylan D., San T., Tufekci U., GENÇ Ş., Ozerdem A.

20th Annual Conference of the International-Society-for-Bipolar-Disorders, Mexico City, Meksika, 7 - 10 Mart 2018, cilt.20, ss.110, (Özet Bildiri)

29. The effects of Dimethyl Fumarate on inflammasome activation in microglial cells

Taştan B., Arıöz B. İ., GENÇ Ş.

5th International Congrees of Molecular Biology Association of Turkey, 8 - 10 Eylül 2017, (Özet Bildiri)

30. mikroRNA ve santral sinir sistemi

GENÇ Ş.

14. Ulusal Sinirbilim Kongresi, 26 - 29 Mayıs 2016

31. expression patterns of micrornas 146a 34a 132 184 in pediatric epilepsy patients

POLAT A. İ., müge a., kemal t., GENÇ Ş., YİŞ U., semra hız k.

31. international epilepsy congress, 5 - 09 Eylül 2015, cilt.56, ss.176, (Özet Bildiri)

32. Expression patterns of microRNAs 146A 34A 132 134 and in pediatric epilepsy patients

POLAT A. İ., Ayanoğlu M., Uğur T., GENÇ Ş., YİŞ U., HIZ A. S.

31. International Epilepsy Congress, 5 - 09 Eylül 2015

33. Sulforaphane exerts protective effects in microglial cells by switching polarization phenotypes

Eren E., Tufekci K. U., Isci K. B., GENÇ Ş.

12th European Meeting on Glial Cell Function in Health and Disease, Bilbao, İspanya, 15 - 18 Temmuz 2015, cilt.63, (Özet Bildiri)

34. A cell division cycle 7-related protein kinase inhibitor suppresses glioblastoma cell growth in vitro

Erkan E. P., Dinc M., Eren E., Allmer J., Yalcin T., GENÇ Ş.

12th European Meeting on Glial Cell Function in Health and Disease, Bilbao, İspanya, 15 - 18 Temmuz 2015, cilt.63, (Özet Bildiri)

35. Endothelial protein C receptor expression in microglia is regulated by Sp1

Tufekci K. U., Eren E., ATEŞ H., GENÇ Ş.

12th European Meeting on Glial Cell Function in Health and Disease, Bilbao, İspanya, 15 - 18 Temmuz 2015, cilt.63, (Özet Bildiri)

36. Antioxidant effect of Lithium is regulated by microRNA-34a in SH-SY5Y cells

Alural B., GENÇ Ş.

40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life, Berlin, Almanya, 4 - 09 Temmuz 2015, cilt.282, ss.219, (Özet Bildiri)

37. Expression patterns of microRNAs 146A 181A and 155 in subacute sclerosing panencephalitis

YİŞ U., Uğur T., GENÇ Ş., Çarman B., BAYRAM E., Yasemin T., et al.

11. European Pediatric Neurology Society Congress, 27 - 30 Mayıs 2015

38. Expression patterns of micro RNAs 146a 181a and 155 insubacute sclerosing panencephalitis

YİŞ U., uğur kemal t., GENÇ Ş., ÇARMAN K. B., BAYRAM E., yasemin t., et al.

11. European Pediatric Neurology Congress, 27 - 30 Mayıs 2015, cilt.19, ss.27, (Özet Bildiri)

39. EXPRESSION PATTERNS OF MICRORNAS-146A,-34A,-132,-134 AND-184 IN PEDIATRIC EPILEPSY PATIENTS

Polat I., Ayanoglu M., Tufekci U., GENÇ Ş., Yis U., Kurul S. H.

31st International Epilepsy Congress, İstanbul, Türkiye, 5 - 09 Eylül 2015, cilt.56, ss.176, (Özet Bildiri)

40. Serum miR 16 levels show negative correlation with amyloid beta1 42 levels in Alzheimer s disease patients

Eren E., Erkan E. P., TÜFEKCİ K. U., Gökçe G., Tanburoğlu A., Demir N., et al.

III. International Congress of the Molecular Biology Association, İzmir, Türkiye, 10 - 12 Eylül 2014, ss.189, (Özet Bildiri)

41. The new cut off for cerebrospinal fluid biomarker of Alzheimer’s disease in the differentiation between FTLD and control subjects for Turkish population

Eren E., KESKİNOĞLU P., TÜFEKÇİ K. U., GÖKÇE G., TANBUROĞLU A., DEMİR N., et al.

Alzheimer’s Association International Conference 2014, 12 - 17 Temmuz 2014, ss.361-362, (Özet Bildiri)

42. Subakut sklerozan panensefalitli hastalarda mikroRNA 146a, 181a ve 155'in ekspresyon paterninin belirlenmesi

YİŞ U., TÜFEKÇİ U., GENÇ Ş., ÇARMAN K. B., TOPÇU Y., BAYRAM E., et al.

16. Ulusal Çocuk Nörolojisi Kongresi, Nevşehir, Türkiye, 22 Haziran 2014, ss.116, (Özet Bildiri)

43. İnsan Beyin Mikrovasküler Endotel Hücrelerinde Hipoksi Reoksijenasyon ile İndüklenen MMP 2 Sekresyonunun Resveratrol Tarafından Azaltılması

ÇAVDAR Z., SAYIN O., ARSLAN N., YÜKSEL EĞRİLMEZ M., ALTUN Z. S., YENER N., et al.

21. ULUSAL BİYOKİMYA KONGRESİ, Türkiye, 28 - 31 Ekim 2009, cilt.34, ss.163-164

44. Resveratrol decreases hypoxia/reoxygenation induced MMP-2 secretion in human brain microvascular endothelial cells

ÇAVDAR Z., Sayin O., Arslan N., Yuksel-Egrilmez M., ALTUN Z. S., Yener N., et al.

34th Congress of the Federation-of-European-Biochemical-Societies, Prague, Çek Cumhuriyeti, 4 - 09 Temmuz 2009, cilt.276, ss.198, (Özet Bildiri)

45. IMATINIB INDUCES AUTOPHAGY THROUGH INCREASING THE EXPRESSION LEVELS OF BECLIN-1 AND ATG-5 GENES IN BOTH PARENTAL SENSITIVE AND IMATINIB-RESISTANT K562 CELLS

Baran Y., Can G., Ekiz H. A., GENÇ Ş.

14th Annual Meeting of the European-Hematology-Association, Berlin, Almanya, 4 - 07 Haziran 2009, cilt.94, ss.233, (Özet Bildiri)

46. The Protective Role of Erytropoietin Against In vitro Ischemia Reperfusion Injury in HUVE Cells In vitro

ALTUN Z. S., İŞLEKEL G. H., YÜKSEL EĞRİLMEZ M., BİÇER N., GENÇ Ş., GENÇ K. K., et al.

Mechanisms, Consequences and Detection of Free Radical-Mediated Oxidative Protein Modifications, Antalya, Türkiye, 15 - 20 Nisan 2009, ss.115

47. Activated protein C attenuates lipopolysaccharide-induced activation of cell death and tumour necrosis factor-alpha production in murine microglial cells

Egrilmez M. Y., ÇAVDAR Z., Genc Ş., Genc K., Guner G.

Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Yunanistan, 28 Haziran - 03 Temmuz 2008, cilt.275, ss.331, (Özet Bildiri)

48. In vitro activation of Nrf2-mediated oxidative stress response in human cerebral microvascular endothelial cells by resveratrol

Arslan N., Edrilmez M. Y., ALTUN Z. S., Sayin O., Genc Ş., Genc K., et al.

Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Yunanistan, 28 Haziran - 03 Temmuz 2008, cilt.275, ss.308, (Özet Bildiri) Sürdürülebilir Kalkınma

49. Hyperoxia causes cell death in the hippocampus of the developing brain

HIZ KURUL S., YİŞ U., KUMRAL A., CİLAKER MIÇILI S., TUĞYAN K., GENÇ Ş., et al.

7th Paediatric Neurology Society (EPNS) Congress, Kuşadası, Türkiye, 26 - 29 Eylül 2007, cilt.11, ss.52, (Tam Metin Bildiri)

50. Hyperoxia causes cell death in the prefrontal cortex of the developing brain

YİŞ U., HIZ KURUL S., KUMRAL A., CİLAKER MIÇILI S., TUĞYAN K., GENÇ Ş., et al.

7th Paediatric Neurology Society (EPNS) Congress, Kuşadası, Türkiye, 26 - 29 Eylül 2007, cilt.11, ss.53, (Tam Metin Bildiri)

51. Effect of in vitro hypoxia and hypoxia/reoxygenation injury on the gelatinases, their inhibitor and activator in endothelial cells

Cavadar Z., Egrlmez M. Y., Genc Ş., Resmi H., Genc K. K., Islekel H., et al.

32nd Congress of the Federation-of-European-Biochemical-Societies (FEBS), Vienna, Avusturya, 7 - 12 Temmuz 2007, cilt.274, ss.360, (Özet Bildiri)

52. Prematüre apnesinde metilksantinlerin akut döneminde beyin hasarı ve uzun dönemde kognitif fonksiyonlar üzerine olan etkisinin araştırılması

KUMRAL A., YEŞİLIRMAK D., AYKAN S., AKHİSARLIOĞLU M., TUĞYAN K., GENÇ Ş., et al.

15.Ulusal Neonatoloji Kongresi, Antalya, Türkiye, 4 - 07 Nisan 2007, (Özet Bildiri)

53. Potential İnteractions Between Neutrophil Apoptosis and Oxidative Damage in Familial Mediterraen Fever FMF

Kırkalı G., Dizdaroğlu M., RESMİ H., Özsan H., TUNCEL E. P., ATEŞ H., et al.

4th İntenational Congress on Systemic Autoinflammatory Diseases, Bethesda, Maryland, USA, 06 Kasım 2004 - 10 Kasım 2006

54. Erythropoietin upregulates NF-E2 related factor 2 expression in astroglial cells in vitro

Aykan S., Egrilmez M., GENÇ Ş., Guner G.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.237, (Özet Bildiri)

55. Erythropoietin-conditioned-astrocyte-conditioned medium decreases ethanol neurotoxicity in vitro

Genc Ş., Kinik E., Bozdag M., Kilic R., Aykan S., Guner G., et al.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.236-237, (Özet Bildiri)

56. The effect of erythropoietin on caspase-8 activation induced by amyloid beta in PC12 cells

Kizildag S., GENÇ Ş., Kizildag S., Sakizli M., Fadiloglu M.

31st Congress of the Federation-of-European-Biochemical-Societies (FEBS), İstanbul, Türkiye, 24 - 29 Haziran 2006, cilt.273, ss.243-244, (Özet Bildiri)

57. Antioksidan diyet, sıçanlarda akut egzersizin eritrosit membran dinamiği üzerindeki etkilerini değiştirir mi

KAYATEKİN B. M., UYSAL HARZADIN N., BEDİZ C. Ş., Temiz-Artmann A., GENÇ Ş., TUĞYAN K., et al.

31.Ulusal Fizyoloji Kongresi, Gaziantep, Türkiye, 1 - 02 Eylül 2005, (Özet Bildiri)

58. The effect of erythropoietin on antioxidant enzymes and nitric oxide in cytokine activated microglial cultures

Kuralay F., Genc Ş., Genc K.

European Congress of Clinical Biochemistry and Laboratory Medicine (EUROMEDLAB 2005), Glasgow, Birleşik Krallık, 8 - 12 Mayıs 2005, cilt.355, (Özet Bildiri)