Circulating exosomal microRNAs in bipolar disorder

Ceylan D., Tufekci K. U., Keskinoğlu P., Genç Ş., Ozerdem A.

JOURNAL OF AFFECTIVE DISORDERS, cilt.262, ss.99-107, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 262
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.jad.2019.10.038
  • Dergi Adı: JOURNAL OF AFFECTIVE DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, ASSIA, PASCAL, AgeLine, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
  • Sayfa Sayıları: ss.99-107
  • Anahtar Kelimeler: Bipolar disorder, MicroRNA, Exosomes, Extracellular vesicles, MAJOR DEPRESSIVE DISORDER, UP-REGULATION, RATING-SCALE, EXPRESSION, DYSREGULATION, RELIABILITY, PATHWAYS, VALIDITY, DISEASE, CORTEX
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: Emerging evidence suggests central roles of miRNAs in the pathogenesis of bipolar disorder (BD). Exosomes are membrane-bound vesicles acing as "biological cargo carriers" of various types of molecules including microRNAs. In this study, we aimed to investigate circulating exosomal microRNAs as potential diagnostic biomarkers for BD.