Circulating exosomal microRNAs in bipolar disorder

Ceylan D., Tufekci K. U., Keskinoğlu P., Genç Ş., Ozerdem A.

JOURNAL OF AFFECTIVE DISORDERS, vol.262, pp.99-107, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 262
  • Publication Date: 2020
  • Doi Number: 10.1016/j.jad.2019.10.038
  • Journal Name: JOURNAL OF AFFECTIVE DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, Academic Search Premier, ASSIA, PASCAL, AgeLine, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Psycinfo, Veterinary Science Database
  • Page Numbers: pp.99-107
  • Keywords: Bipolar disorder, MicroRNA, Exosomes, Extracellular vesicles, MAJOR DEPRESSIVE DISORDER, UP-REGULATION, RATING-SCALE, EXPRESSION, DYSREGULATION, RELIABILITY, PATHWAYS, VALIDITY, DISEASE, CORTEX
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction: Emerging evidence suggests central roles of miRNAs in the pathogenesis of bipolar disorder (BD). Exosomes are membrane-bound vesicles acing as "biological cargo carriers" of various types of molecules including microRNAs. In this study, we aimed to investigate circulating exosomal microRNAs as potential diagnostic biomarkers for BD.