Examination of IL-1 beta level as an inflammasome marker in Alzheimer's disease


Bulut O., Tanburoglu A., Boluk G., Demir N., Eren E., Vurgun U., ...More

NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY, vol.36, no.3, pp.141-147, 2019 (SCI-Expanded, Scopus, TRDizin)

  • Publication Type: Article / Article
  • Volume: 36 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.5152/nsn.2019.10324
  • Journal Name: NEUROLOGICAL SCIENCES AND NEUROPHYSIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.141-147
  • Keywords: Alzheimer's disease, cytokine, dementia, enzyme linked immunosorbent assay, interleukin-1 beta
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Interleukin (IL)-1 beta is believed to be responsible for the neurotoxicity of amyloid plaques in Alzheimer's disease (AD). In the present study, serum levels of IL-1 beta, and correlations with clinical features and neuropsychiatric test results were examined.