The Effect of Erythropoietin on Neurotrophic Factors in N9 Murine Microglial Cells
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.38, no.6, pp.519-524, 2008 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 38 Issue: 6
- Publication Date: 2008
- Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.519-524
- Keywords: Microglia, N9 cell line, murine, erythropoietin, neurotrophic factors
- Dokuz Eylül University Affiliated: Yes
Abstract
Aim: In this study, we investigated whether interferon gamma (IFN gamma). lipopolysaccharides (LPS) and amyloid beta (AMY beta), as toxic stimulator agents, and erythropoietin (EPO), as a neurotrophic agent. have an effect on the production of the following neurotrophic factors in the N9 murine microglia cell line: neurotrophin 3 (NT3), neurotrophin 4 (NT4), and brain-derived neurotrophic factor (BDNF).