The Effect of Erythropoietin on Neurotrophic Factors in N9 Murine Microglial Cells
TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.38, sa.6, ss.519-524, 2008 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 38 Sayı: 6
- Basım Tarihi: 2008
- Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.519-524
- Anahtar Kelimeler: Microglia, N9 cell line, murine, erythropoietin, neurotrophic factors
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Aim: In this study, we investigated whether interferon gamma (IFN gamma). lipopolysaccharides (LPS) and amyloid beta (AMY beta), as toxic stimulator agents, and erythropoietin (EPO), as a neurotrophic agent. have an effect on the production of the following neurotrophic factors in the N9 murine microglia cell line: neurotrophin 3 (NT3), neurotrophin 4 (NT4), and brain-derived neurotrophic factor (BDNF).