The Role of MicroRNAs in Biological Processes

Tufekci K. U., Meuwissen R. L. J., GENÇ Ş.

MIRNOMICS: MICRORNA BIOLOGY AND COMPUTATIONAL ANALYSIS, cilt.1107, ss.15-31, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1107
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/978-1-62703-748-8_2
  • Dergi Adı: MIRNOMICS: MICRORNA BIOLOGY AND COMPUTATIONAL ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.15-31
  • Anahtar Kelimeler: Apoptosis, Immune responses, MicroRNA, Cell signaling, Development, Differentiation, Autophagy, PROSTATE-CANCER, APOPTOSIS, EXPRESSION, GENE, AUTOPHAGY, TARGETS, MOUSE, MODULATION, SUPPRESSOR, CELLS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

MicroRNAs (miRNAs) are tiny regulators of gene expression on the posttranscriptional level. Since the discovery of the first miRNA 20 years ago, thousands of them have been described. The discovered miRNAs have regulatory functions in biological and pathological processes. Biologically, miRNAs have been implicated in development, differentiation, proliferation, apoptosis, and immune responses. In this work, we summarize the role of miRNA in biological processes taking into account the various areas named above.