TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.35, sa.3, ss.195-202, 2010 (SCI-Expanded)
Aim: In the course of ischemia reperfusion, injury / functional deterioration of the endothelium contribute to tissue damaging process. Hypoxia-reoxygenation model has been used as in vitro model of ischemia reperfusion injury. Oxygen glucose deprivation model can be considered to mimic the in vivo conditions. This study aimed to develop an in vitro model of ischemia reperfusion injury in human brain micro vascular endothelial cells and to evaluate the cell injury caused.