ASSOCIATION OF PERIPHERAL VISFATIN LEVELS AND VISFATIN G-948T GENE POLYMORPHISM WITH ALZHEIMER'S DISEASE IN A TURKISH POPULATION

Vurgun U., Sahin O., Tufekci K. U., Keskinoğlu P., Yener G., Genc K. K., ...More

TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI, vol.16, no.2, pp.123-128, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2013
  • Journal Name: TURKISH JOURNAL OF GERIATRICS-TURK GERIATRI DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.123-128
  • Keywords: Nicotinamide Phosphoribosyltransferase, Alzheimer Disease, Polymorphism, Inflammation, Aging, COLONY-ENHANCING FACTOR, ISCHEMIC-STROKE, PLASMA-LEVELS, TYPE-2, OBESE, INFLAMMATION, PROMOTER
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction: Visfatin is a pleiotropic cytokine implicated in several physiological and pathophysiological processes such as innate immunity, cellular metabolism, longevity, and inflammation. Altered visfatin levels and visfatin gene polymorphisms have been reported in various human diseases, including type 2 diabetes mellitus, rheumatoid arthritis, obesity, coronary artery disease and stroke..