PHYTOMEDICINE, vol.75, 2020 (SCI-Expanded)
Article / Review
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
Phytochemical, NLRP3 inflammasome, Curcumin, Resveratrol, Sulforaphane, ISCHEMIA/REPERFUSION INJURY, ADIPOSE-TISSUE, RESVERATROL, CURCUMIN, RATS, CELLS, PROTECTS, PATHWAY, SIRT1
Dokuz Eylül University Affiliated:
Background: The NLRP3 inflammasome formation and following cytokine secretion is a crucial step in innate immune responses. Internal and external factors may trigger inflammasome activation and result in inflammatory cytokine secretion. Inflammasome formation and activity play critical roles in several disease pathologies such as cardiovascular, metabolic, renal, digestive, and CNS diseases. Underlying pathways are not yet clear, but phytochemicals as alternative therapies have been extensively used for suppression of inflammatory responses.