Chiral separation of amino acids using a chiral crown ether by impregnation on a polymeric support and monoamine modified silica gel

Seyhan S., Turgut Y., MERDİVAN M., Hosgoren H.

TETRAHEDRON-ASYMMETRY, cilt.17, sa.11, ss.1700-1704, 2006 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 11
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.tetasy.2006.06.008
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1700-1704
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

A chiral monoaza-15-crown-5 ether derivative was prepared from L-Leucinol and used as a chiral stationary phase. The new chiral stationary phases CSP-1 and CSP-2 were employed in separating the enantiomers of the sodium and potassium salts of amino acids. The sodium and potassium salt of the D-enantiomers of all amino acids (PhyAlaNa, PhyAlaK and PhyGlyNa, PhyGlyK, and TrpNa, TrpK) show higher selectivity than the L-enantiomers for both CSP-1 and CSP-2. (c) 2006 Elsevier Ltd. All rights reserved.