Identification of Transcriptional and Metabolic Programs Related to Mammalian Cell Size

Mlettinen, Teemu; Pessa, Heli; Caldez, Matias; Fuhrer, Tobias; DİRİL, MUHAMMED; Sauer, Uwe; Kaldis, Philipp; Bjoerklund, Mikael

doi:10.1016/j.cub.2014.01.071

Identification of Transcriptional and Metabolic Programs Related to Mammalian Cell Size

Mlettinen T. P., Pessa H. K. J., Caldez M. J., Fuhrer T., DİRİL M. K., Sauer U., ...Daha Fazla

CURRENT BIOLOGY, cilt.24, sa.6, ss.598-608, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 24 Sayı: 6
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.cub.2014.01.071
Dergi Adı: CURRENT BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.598-608
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: Regulation of cell size requires coordination of growth and proliferation. Conditional loss of cyclin-dependent kinase 1 in mice permits hepatocyte growth without cell division, allowing us to study cell size in vivo using transcriptomics and metabolomics.