Pemphigoid gestationis: Light microscopic and direct immunofluorescense findings Gestasyonel pemfigoid: Işik mikroskopik ve direkt Immünflöresan bulgulari

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Niflioǧlu G. G., LEBE B.

Turk Patoloji Dergisi/Turkish Journal of Pathology, cilt.30, sa.2, ss.152-154, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5146/tjpath.2013.01172
  • Dergi Adı: Turk Patoloji Dergisi/Turkish Journal of Pathology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.152-154
  • Anahtar Kelimeler: Gestational pemphigoid, Pregnancy, Skin diseases, Vesiculobullous
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Pemphigoid gestationis is a rare vesiculobullous dermatosis of pregnancy and puerperium. It is commonly seen in second or third trimester. Skin lesions are characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae. Histopathology demonstrates a subepidermal eosinophil-rich vesiculation. Direct immunofluorescence microscopy reveals linear complement 3 and immunoglobulin G deposition along the basement membrane. We present a rare case of pemphigoid gestationis occurring in a 33-year-old pregnancy woman with symptom of generalized pruritis. Pemphigoid gestationis should be kept in mind in the differential diagnosis of vesiculobullous dermatitis of pregnancy.