Pemphigoid gestationis: Light microscopic and direct immunofluorescense findings Gestasyonel pemfigoid: Işik mikroskopik ve direkt Immünflöresan bulgulari


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Niflioǧlu G. G., LEBE B.

Turk Patoloji Dergisi/Turkish Journal of Pathology, vol.30, no.2, pp.152-154, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 2
  • Publication Date: 2014
  • Doi Number: 10.5146/tjpath.2013.01172
  • Journal Name: Turk Patoloji Dergisi/Turkish Journal of Pathology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.152-154
  • Keywords: Gestational pemphigoid, Pregnancy, Skin diseases, Vesiculobullous
  • Dokuz Eylül University Affiliated: Yes

Abstract

Pemphigoid gestationis is a rare vesiculobullous dermatosis of pregnancy and puerperium. It is commonly seen in second or third trimester. Skin lesions are characterized by pruritic, urticarial plaques with the development of tense vesicles and bullae. Histopathology demonstrates a subepidermal eosinophil-rich vesiculation. Direct immunofluorescence microscopy reveals linear complement 3 and immunoglobulin G deposition along the basement membrane. We present a rare case of pemphigoid gestationis occurring in a 33-year-old pregnancy woman with symptom of generalized pruritis. Pemphigoid gestationis should be kept in mind in the differential diagnosis of vesiculobullous dermatitis of pregnancy.