Hematological indices in children with upper respiratory tract infections
2nd International Critical Care and Emergency Medicine Congress, Antalya, Türkiye, 16 - 19 Nisan 2015, ss.139, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Antalya
- Basıldığı Ülke: Türkiye
- Sayfa Sayıları: ss.139
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
BACKGROuND: Acute upper respiratory tract infections (URTIs) contribute substantially to pediatric morbidity and mortality worldwide. Prevention of these infections in childhood is a very important public health challenge. This study was performed to determine the associaiton between hematological indices and URTI. METhODS: Thirty patients with URTI (diagnosed as tonsillitis, pharyngitis, sinusitis, otitis media) and 41 healthy controls were included to this retrospective study. Hematologic data of these subjects were obtained from their medical records. Groups were compared in terms of white blood cell (WBC) mean platelet volume (MPV), platelet distribution width (PDW) and red cell distribution width (RDW). RESULTS: Average ages of groups were 33,7±24,18 and 20,21±16,21 months in patient and control groups. Mean values of WBC, MPV, PDW and RDW were 11,5±6,08, 8,08±0,92, 12,22±1,38 and 13,39±1,14 in URTI group and 9,65±3,11, 7,35±0,88, 10,86±2,01 and 12,28±1,06 in control subjects retrospectively. Patients with URTI had higher MPV (p:0.01), PDW (p:0.02) and RDW (p<0.001) values than healthy subjects. Area under the curve (AUC) for MPV was 0,750±0,058 (0.637 – 0.863), AUC for PDW was 0,723±0,062 (0.603 – 0.844) and AUC for RDW was 0,751±0,059 (0.635 – 0.867) (Figure 1). CONCLuSION: Our data did not support a relationship for WBC values between URTI and healthy controls. However, a statistically significant higher MPV, PDW and RDW was detected in the subjects with URTI. MPV, PDW and RDW are routinely measured parameters in complete blood count and requires no additional cost and they might be used as new and convenient markers for children with URTI.