Akademik Veri Yönetim Sistemi
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL, cilt.13, sa.3, ss.111-114, 2008 (ESCI)
Chronic hepatitis B infection is an important disease that can cause cirrhosis, hepatocellular carsinoma and death. Hepatitis B virus (HBV) is transmitted by four main routes; parenteral contact {percutaneous) with infected blood and body fluids, sexual contact, infection of an infant born to infected mother {perinatalvertical) and close contact with infected people without sexuality (horizontal}. In this study, we analyzed the risk factors related to hepatitis B infection in 202 HBsAg positive patients admitted to the Infectious Diseases and Clinical Microbiology Policlinic of Gaziosmanpasa University Hospital between July 2007 and February 2008. Medical history of the patients revealed that 129 patients had dental treatment (63.9%), 7I patients had an operation (35. 1%), 33 patients were born to hepatitis B-infected mothers (16.3%), 15 patients had hospitalization for Ianger than one week (7.4%}, 9 patients had hepatitis B-infected fathers {4.5%), 8 patients had endoscopy and 8 patients had angiography (% 4), 33 female patients had curettage (55%). Twenty female patients (33.3%} had at least one HBsAg positive children, whereas II male patients (10.2%) had at least one HBsAg positive children (p<0.05). Positivity of anti-HBe was determined as 89.6%. Although percutaneous transmission route was determined to be the most important risk factor, perinatal vertical transmission had also an important role. Therefore, it should not be forgotten that pregnant women must be examined regarding the presence of HBsAg and hepatitis B immunglobulin must be applied with the vaccine at birth to the infant born to HBsAg positive mother.