Primary platinum resistance and its prognostic impact in patients with recurrent ovarian cancer: an analysis of three prospective trials from the NOGGO study group


Trillsch F., Mahner S., Czogalla B., Rottmann M., Chekerov R., Braicu E. I., ...More

JOURNAL OF GYNECOLOGIC ONCOLOGY, vol.32, no.3, 2021 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 32 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.3802/jgo.2021.32.e37
  • Journal Name: JOURNAL OF GYNECOLOGIC ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE
  • Keywords: Recurrent Ovarian Cancer, Primary Platinum Resistance, Mono-chemotherapy, Anti-angiogenic Treatment, Sorafenib, Prognostic Factor
  • Dokuz Eylül University Affiliated: No

Abstract

Objective: Patients with platinum-resistant ovarian cancer (PROC) have a high need for reliable prognostic markers. Since significance of primary platinum resistance (PPR) versus secondary platinum resistance (SPR) was identified for patients receiving anti-angiogenic therapy, it has not been confirmed for chemotherapy only.