Drug-Eluting Balloon Angioplasty for Juxta-Anastomotic Stenoses in Distal Radiocephalic Hemodialysis Fistulas: Long-Term Patency Results


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Gülcü A., Sarioglu O., Peker A., Alataş Ö.

CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, no.6, pp.835-840, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2019
  • Doi Number: 10.1007/s00270-019-02213-w
  • Journal Name: CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.835-840
  • Keywords: Drug-eluting balloon, Percutaneous transluminal angioplasty, Juxta-anastomotic stenosis, ARTERIOVENOUS-FISTULAS, ENDOVASCULAR TREATMENT, PERIANASTOMOTIC STENOSIS, ACCESS, PACLITAXEL, GRAFTS, RESTENOSIS, MANAGEMENT, OUTCOMES, SALVAGE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: To evaluate long-term primary and secondary patency results of drug-eluting balloon angioplasty for the treatment of juxta-anastomotic stenoses in distal radiocephalic arteriovenous fistulas. Materials and Methods: Thirty-eight patients with juxta-anastomotic stenotic distal radiocephalic arteriovenous fistulas who underwent endovascular treatment with drug-eluting balloons between January 2014 and August 2016 in our interventional radiology department were included in this retrospective study. Color Doppler examination for follow-up was performed 15 days, 6 months, 12 months, 18 months, 24 months, 36 months, and 48 months after the procedure. Kaplan-Meier analysis was used to estimate primary and secondary patency rates. Results: Totally, 42 angioplasty with drug-eluting balloons was performed in 38 patients (20 men and 18 women; mean age 66.42 +/- 12.01). Technical and clinical success rate was 100% (42/42). The mean follow-up period was 27.71 months +/- 12.98 (range, 1-54 months). The estimated primary patency rates at 6 months were 94.7% (95% CI, 80.9%-99.0%), at 12 months were 81.2% (95% CI, 64.6%-91.4%), at 24 months were 60.7% (95% CI, 43.6%-75.7%), and at 48 months were 53.1% (95% CI, 36.5%-69.1%). The estimated secondary patency rates at 6 months were 97.3% (95% CI, 84.5%-99.8%), at 12months were 86.5% (95% CI, 70.7%-94.8%), at 24 months were 69.0% (95% CI, 51.8%-82.4%), and at 48 months were 61.7% (95% CI, 44.6%-76.5%). Conclusion: Durg-eluting balloon angioplasty is a useful, effective technique in dysfunctional radiocephalic fistulas due to juxta-anastomotic stenoses. We demonstrated remarkably high primary patency rates at 6, 12, 24, and 48 months.