The Etiopathogenesis of Autoimmune Bullous Diseases


Aktan Ş.

TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, vol.45, pp.8-15, 2011 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45
  • Publication Date: 2011
  • Doi Number: 10.4274/turkderm.45.s3
  • Journal Name: TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.8-15
  • Keywords: Autoimmune disease, skin diseases, vesiculobullous, pemphigus, pemphigoid, bullous, benign mucous membrane, laminin gamma 1, pemphigoid gestationis, dermatitis herpetiformis, immunoglobulin A, dermatosis, epidermolysis bullosa acquisita
  • Dokuz Eylül University Affiliated: Yes

Abstract

Autoimmune bullous diseases are rare disorders affecting skin and mucous membranes which are mediated by pathogenic autoantibodies against target antigens whose function is adhesion within the epidermis or adhesion of epidermis to dermis. The pathogenesis of these disorders has been extensively investigated with advanced techniques in recent years. This review focuses on the etiopathogenesis of main autoimmune bullous disorders including pemphigus, bullous pemphigoid, anti-p200 pemphigoid, cicatricial pemphigoid, pemphigoid gestationis, dermatitis herpetiformis, linear IgA bullous dermatosis and epidermolysis bullosa acquisita.