EVALUATION OF PEDIATRIC EMERGENCY TRAUMA PATIENTS FOR ACUTE TRAUMATIC COAGULOPATHY

Eriş G., Ulusoy E., Er A., Eser Ö., Duman M., Tüfekçi Gürocak Ö., ...Daha Fazla

The 33rd Congress of the International Society on Thrombosis and Haemostasis, Washington, Amerika Birleşik Devletleri, 21 - 25 Haziran 2025, ss.135-136, (Özet Bildiri)

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Washington
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Sayfa Sayıları: ss.135-136
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: Acute traumatic coagulopathy (ATC) is common in severe traumas and an important cause of mortality.

Objective: We aimed to investigate the incidence and characteristics of ATC which may develop in pediatric trauma patients and evaluate the risk factors affecting prognosis and outcome.

Materials and Methods: Pediatric trauma patients admitted to our Pediatric Emergency Care Unit between January 1, 2015 and June 1, 2023 were included. Demographics, presence of chronic diseases, clinical and laboratory features at admission, radiological examination results, treatment and follow-up notes, prognosis, and causes of mortality and morbidity were obtained from the patients’ hospital records.

Results: Data from 1071 patients were analyzed. The incidence of ATC was 30.9%. Statistical analysis of the patients' findings revealed that a Glasgow Coma Score of ≤8, an ISTH DIC score of ≥5, presence of abnormal vital signs, anemia, and need for blood transfusion were identified as the most important independent risk factors for predicting the development of ATC. On follow-up, 0.7% of the patients developed intracranial hemorrhage. The presence of thrombocytopenia, as well as elevated aPTT and PT, were identified as the most significant risk factors. The mortality rate in patients with ATC was 6.3%, and the presence of hemorrhage due to ATC increased mortality by 8.1 times. Hypercoagulopathic events developed in 2.6% of the patients. Thrombotic events were most commonly located in the cerebral region (53.6%).  The presence of abnormal vital signs at admission, traumatic brain injury, and the development of ATC on the background of chronic illness were found to increase the risk of hypercoagulopathic events. The mortality rate in these patients was 7.1%. The rate of neurologic sequelae was 24.5 times higher in patients who developed ATC compared to those who did not.

Conclusion: In pediatric trauma patients, ATC may lead to increased mortality and long-term neurologic sequelae.