Cefixime-Induced Oculogyric Crisis

Bayram E., TORUN BAYRAM M., HIZ A. S., Turkmen M.

PEDIATRIC EMERGENCY CARE, vol.28, no.1, pp.55-56, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1097/pec.0b013e31823f252d
  • Journal Name: PEDIATRIC EMERGENCY CARE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.55-56
  • Keywords: oculogyric crisis, side effect, cefixime, CEFEPIME-INDUCED ENCEPHALOPATHY, NORMAL RENAL-FUNCTION, DYSTONIC REACTION, THERAPY, CETIRIZINE, DISORDERS, PATIENT
  • Dokuz Eylül University Affiliated: Yes

Abstract

Oculogyric crisis is a neurologic adverse event characterized by bilateral dystonic, usually upward, conjugate eye deviations. Cefixime is a third-generation cephalosporin and is widely used in clinical practice in childhood. Confusion, encephalopathy, coma, myoclonus, nonconvulsive status epilepticus, and seizures have been described with the use of cephalosporins. We presented a cefixime-induced oculogyric crisis in a 7-year-old boy during the treatment of urinary tract infection, and this is the first case of cefixime-induced oculogyric crisis whose ocular symptoms gradually disappeared within 48 hours after the drug was discontinued.