Expression of CD44 and major histocompatibility complex class II antigens correlate with renal scarring in primary and systemic renal diseases


Kirimca F., SARIOĞLU S., Camsari T., Kavukcu S.

SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, vol.35, no.6, pp.509-514, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2001
  • Doi Number: 10.1080/003655901753367640
  • Journal Name: SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.509-514
  • Keywords: CD44, chronic pyelonephritis, MHC class II antigens, morphometry, renal scarring, TUBULOINTERSTITIAL FIBROSIS, LUPUS NEPHRITIS, PROGRESSION, CELLS, PATHOGENESIS, CYTOKINES, KIDNEYS, MICE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Phenotypical changes in the tubular epithelial cells (TEC) seem to be important in the progression of renal diseases. The present study was designed to identify the relation between the expression of major histocompatibility complex (MHC) class II antigens and CD44 by TEC, with parameters of renal scarring in primary and systemic renal diseases.