Development of biological meniscus scaffold: Decellularization method and recellularization with meniscal cell population derived from mesenchymal stem cells
JOURNAL OF BIOMATERIALS APPLICATIONS, vol.35, no.9, pp.1192-1207, 2021 (SCI-Expanded)
- Publication Type: Article / Article
- Volume: 35 Issue: 9
- Publication Date: 2021
- Doi Number: 10.1177/0885328220981189
- Journal Name: JOURNAL OF BIOMATERIALS APPLICATIONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
- Page Numbers: pp.1192-1207
- Keywords: Meniscus, decellularization, recellularization, mesenchymal stem cells, fibrochondrocytes, tissue engineering
- Dokuz Eylül University Affiliated: Yes
Abstract
Tissue engineering approaches which include a combination of cells and scaffold materials provide an alternative treatment for meniscus regeneration. Decellularization and recellularization techniques are potential treatment options for transplantation. Maintenance of the ultrastructure composition of the extracellular matrix and repopulation with cells are important factors in constructing a biological scaffold and eliminating immunological reactions.