Development of biological meniscus scaffold: Decellularization method and recellularization with meniscal cell population derived from mesenchymal stem cells

Kara A., Koçtürk A. S., Bilici G., Havıtçıoğlu H.

JOURNAL OF BIOMATERIALS APPLICATIONS, cilt.35, sa.9, ss.1192-1207, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1177/0885328220981189
  • Dergi Adı: JOURNAL OF BIOMATERIALS APPLICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1192-1207
  • Anahtar Kelimeler: Meniscus, decellularization, recellularization, mesenchymal stem cells, fibrochondrocytes, tissue engineering
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Tissue engineering approaches which include a combination of cells and scaffold materials provide an alternative treatment for meniscus regeneration. Decellularization and recellularization techniques are potential treatment options for transplantation. Maintenance of the ultrastructure composition of the extracellular matrix and repopulation with cells are important factors in constructing a biological scaffold and eliminating immunological reactions.