Hypovitaminosis Dand orthostatic hypotension: a systematic review and meta-analysis


Ometto F., Stubbs B., Annweiler C., Duval G. T., Jang W., Kim H., ...More

JOURNAL OF HYPERTENSION, vol.34, no.6, pp.1036-1043, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 34 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.1097/hjh.0000000000000907
  • Journal Name: JOURNAL OF HYPERTENSION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1036-1043
  • Keywords: meta-analysis, orthostatic hypotension, serum 25 hydroxyvitamin D, vitamin D, VITAMIN-D DEFICIENCY, BLOOD-PRESSURE, 1,25-DIHYDROXYVITAMIN D-3, INDUCED NEUROTOXICITY, 25-HYDROXYVITAMIN D, D SUPPLEMENTATION, RISK, HYPERTENSION, ASSOCIATION, MORTALITY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objectives: Orthostatic hypotension is a common condition among older adults and is associated with a range of deleterious outcomes. Recently, interest has developed in hypovitaminosis D (defined as low 25 hydroxiyvitamin D levels) as a potential risk factor for orthostatic hypotension. We conducted a systematic review and meta-analysis examining the association of orthostatic hypotension between study participants with and without hypovitaminosis D, including the adjustment of potential confounders (age, sex, BMI, renal function, comorbidities, seasonality, use of antihypertensive medications, and supplementation with cholecalciferol).