Increased expression of VEGF, iNOS, IL-1 beta, and IL-17 in a rabbit model of gastric content-induced middle ear inflammation

Basoglu, M.; Eren, Erdem; Aslan, Hale; KOLATAN, HATİCE; Ozbay, Can; Inan, Sevinc; Karaca, Fatma; Ozturkcan, Sedat; Katilmis, Huseyin

doi:10.1016/j.ijporl.2011.10.001

Increased expression of VEGF, iNOS, IL-1 beta, and IL-17 in a rabbit model of gastric content-induced middle ear inflammation

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Basoglu M. S., Eren E., Aslan H., KOLATAN H. E., Ozbay C., Inan S., ...More

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, vol.76, no.1, pp.64-69, 2012 (SCI-Expanded)

Publication Type: Article / Article
Volume: 76 Issue: 1
Publication Date: 2012
Doi Number: 10.1016/j.ijporl.2011.10.001
Journal Name: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.64-69
Keywords: VEGF, iNOS, IL-1 beta, IL-17, Gastric content, Inflamation, ENDOTHELIAL GROWTH-FACTOR, EXPERIMENTAL OTITIS-MEDIA, GASTROESOPHAGEAL-REFLUX, NITRIC-OXIDE, EFFUSION, CHILDREN, INTERLEUKIN-1-BETA, DISORDERS
Dokuz Eylül University Affiliated: Yes

Abstract

Objective: To investigate the histopathological changes and the expression of vascular endothelial growth factor (VEGF), inducible NO-synthase (iNOS), endothelial NO-synthase (eNOS), interleukin (IL)-1 beta, and IL-17 in the rabbit middle ear mucosa after direct gastric content exposure.