Evaluation of (99m)Technetium-Vancomycin Imaging Potential in Experimental Rat Model for the Diagnosis of Infective Endocarditis


Kis T. T., Kose Ş., YILMAZ O., Kis M., YURT ONARAN F., Acar E., ...More

CURRENT MEDICAL IMAGING, vol.17, no.6, pp.781-789, 2021 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 17 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.2174/1573405616666201229161850
  • Journal Name: CURRENT MEDICAL IMAGING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.781-789
  • Keywords: Infective endocarditis, technetium-99m, vancomycin, T/Nt ratio, scintigraphy, imaging, SCINTIGRAPHY, BIODISTRIBUTION, VANCOMYCIN, CONFER, AGENT
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background: Infective endocarditis (IE) is an infection of the heart's endocardial surface. In recent years, nuclear imaging methods have gained importance in the diagnosis of IE. The present study aims to investigate the imaging potential of Tc-99m-labeled vancomycin (Tc-99m-Van-comycin) as a new agent that would enable the diagnosis of IE in its early stages when it is difficult to diagnose or has small vegetation in the experimental rat model.