Akademik Veri Yönetim Sistemi
Turkiye Klinikleri Dermatoloji, cilt.21, sa.2, ss.103-106, 2011 (Scopus)
The Leser-Trélat (LT) sign is characterized by the sudden appearance and rapid incre ase in number and size of pruritic multiple seborrheic keratoses within a short period of time. Al though it has been described in association with a variety of malignancies, the reliability of the LT sign as a paraneoplastic marker has been questioned in the literature. Commonly associated malig nancies include adenocarcinomas of the gastrointestinal tract, particularly in the stomach or co lon, but also others including squamous cell carcinoma, lymphoma and leukaemias may be observed. However, appearance of the LT sign in genitourinary malignancies is rare. We report a 84 year old man with the sudden onset and dramatic increase of the pruritic seborrheic keratoses along with a prostate adenocarcinoma. Our case is presented to emphasize the necessity of comprehensive din ical, laboratory and radiologic investigations when considered LT sign. Copyright © 2011 by Türkiye Klinikleri.