The Relationship Between Lithium and Cancer Proliferation: A Case-Based Review of the Literature.

Ozerdem A., Ceylan D., Targitay B.

Current drug metabolism, cilt.19, sa.8, ss.653-662, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 8
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1389200219666180430095933
  • Dergi Adı: Current drug metabolism
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.653-662
  • Anahtar Kelimeler: Lithium, cancer proliferation, urinary tract cancer, tumor, GSK-3, redox modulations, mitochondrial damage, GLYCOGEN-SYNTHASE KINASE-3, RENAL-CELL CARCINOMA, OXIDATIVE STRESS MARKERS, INDUCED DNA-DAMAGE, FACTOR-KAPPA-B, BIPOLAR DISORDER, VALPROIC ACID, HISTONE DEACETYLASE, IN-VITRO, MITOCHONDRIAL DYSFUNCTION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: The incidence and mortality rates of cancer in patients with Bipolar Disorder (BD) is higher compared with the general population. The role of Lithium (Li) in cancer proliferation/inhibition is still a controversial issue in the literature.