The effect of diclofenac on matrix metalloproteinase levels in the rotator cuff


Cabuk H., Avci A., Durmaz H., Cabuk F. K., Ertem F., Sener I. M.

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, vol.134, no.12, pp.1739-1744, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 134 Issue: 12
  • Publication Date: 2014
  • Doi Number: 10.1007/s00402-014-2099-0
  • Journal Name: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1739-1744
  • Keywords: Diclofenac, Matriks metalloprotinase, Rotator cuff, Tendon healing, Biomechanic, GENE-EXPRESSION, TENDONS, SUPRASPINATUS, TEAR
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction Matrix metalloproteinases (MMPs) are involved in physiological events such as restructuring of the tissue, morphogenesis, wound healing and normal developmental process. Use of diclofenac sodium following rotator cuff repair can disrupt healing of tendon through acting on MMPs.