Myelolipomatous changes within adrenocortical adenoma

Firat C., Eryigit S., Yener S., DEMİR T., BOZKURT O., Demir O., ...More

CUKUROVA MEDICAL JOURNAL, vol.44, no.3, pp.1135-1138, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.17826/cumj.494051
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1135-1138
  • Keywords: Adenoma, adrenal, cortical, myelolipoma, non-functional, ADRENAL MYELOLIPOMA, HEMATOPOIETIC ELEMENTS
  • Dokuz Eylül University Affiliated: Yes


Myelolipoma is a rare benign tumor which is generally detected incidentally. The tumor consists of mature fat tissue and hematopoietic cells that resemble bone marrow. The coexistence of myelolipoma and nonfunctional adrenocortical adenoma in the same gland is exceedingly rare. We herein present two cases of adrenal myelolipoma in association with non-functional adrenocortical adenoma in left adrenal gland of a 62-year-old woman and non-functional adrenocortical adenoma combined with myelolipoma and endothelial cyst, in right adrenal gland of a 73-years-old man. Microscopically, in the central of the tumor, there was a myelolipomatous area composed of adipocytes and hematopoietic cells surrounded by sheets of adenoma cells. The histopathological diagnosis was "myelolipomatous changes within a non-functional adrenocortical adenoma". The cases are presented here with their rarity and pathological differential diagnosis.