Purpose: The objective of this study was to determine the prevalence of fibromyalgia on persons who work in a static posture and to investigate the efficiency of two different exercise programs. Material and methods: This study was conducted in Dokuz Eylül University School of Physical Therapy and Rehabilitation on 32 patients who were diagnosed according to the American College of Rheumatology Fibromyalgia Classification Criterias and who work in a static posture using a computer and typing. The first group (16 patients) received stretching, posture and strengthening exercises, the second group (16 patients) received remedial exercise, post-isometric relaxation and self mobilization for three weeks and three sessions in one week. All patients received moist heat before exercises and were educated for posture awareness. Before and after treatment cervical and spinal flexibility was evaluated and the Fibromyalgia Impact Questionnaire was applied. Results: The estimated prevalence of fibromyalgia was 26.6 % in 150 persons who worked in a static posture using a computer and typing. Evaluations were made before and after treatment and improvements were noted for both groups (p<0.05). After treatment no significant difference was seen between the improvements of the two groups (p>0.05). Conclusion: We can conclude that both these two different exercise programs are effective in the treatment of fibromyalgia.