JAK2 V617F Mutation Status of 232 Patients Diagnosed With Chronic Myeloproliferative Neoplasms

Payzin K. B., Savasoglu K., ALACACIOĞLU İ., Ozdemirkiran F., Mutlu B. B., Bener S., ...More

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, vol.14, no.6, pp.525-533, 2014 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1016/j.clml.2014.02.013
  • Journal Name: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.525-533
  • Keywords: Essential thrombocythemia, JAK2 mutation, MPNs, Polycythemia vera, Primary myelofibrosis
  • Dokuz Eylül University Affiliated: Yes

Abstract

The aim of this study was to investigate the presence of Janus kinase 2 (JAK2) V617F mutation in patients with BCR-ABL negative chronic myeloproliferative neoplasms (CMPNs) in our center. JAK2 V617F mutation frequencies in our PV and ET patients were similar to those reported previously. JAK2 V617F mutation frequency in our PMF patients was greater than in previous reports.