Impact of molecular allergy tests on diagnosis and treatment of eosinophilic esophagitis


Baysal Bakır D., Uzuner N., Atay Ö., Yağmur H., Kabadayı G.

Food Allergy and Anaphylaxis Meeting & European Consortium on Application of Flow Cytometry in Allergy, Athens, Yunanistan, 21 - 23 Kasım 2024, (Yayınlanmadı)

  • Yayın Türü: Bildiri / Yayınlanmadı
  • Basıldığı Şehir: Athens
  • Basıldığı Ülke: Yunanistan
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The analysis of multiple molecular components is recognized as a third-level diagnostic tool in allergen sensitization, following the Skin Prick Test (SPT) and specific IgE (sIgE) testing. Multiplex tools are believed to assist clinicians in differentiating between clinically relevant sensitizations and less relevant ones and in clarifying the etiology of mixed-type reactions such as eosinophilic esophagitis (EoE). ALEX (Allergy Explorer, Macro Array Diagnostics, Vienna, Austria), a new molecular multiplex array for allergy diagnostics today, launched and commercially available in 2019, represents an expanded platform offering comprehensive molecular components of allergen sources. We aimed to present 2 cases to discuss the current state of allergy testing for patients with EoE and to emphasize the importance of using molecular allergy tests in diagnosing and making treatment decisions for EoE patients, particularly in individuals with atopy.