Medullary sponge kidney associated with distal renal tubular acidosis in a 5-year-old girl

Kasap B., SOYLU A., Oren O., Turkmen M., Kavukcu S.

EUROPEAN JOURNAL OF PEDIATRICS, cilt.165, sa.9, ss.648-651, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 165 Sayı: 9
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1007/s00431-006-0125-0
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.648-651
  • Anahtar Kelimeler: medullary sponge kidney, distal renal tubular acidosis, proximal renal tubular dysfunction, growth retardation, GROWTH-FACTOR, DYSFUNCTION, DEFECTS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: Medullary sponge kidney (MSK) is characterized by cystic dilatation of the inner medullary collecting ducts, which causes the kidneys to resemble a sponge. Case report: Although distal renal tubular acidosis (dRTA) is commonly observed in patients with MSK, we report a 5-year-old girl with MSK who had features of both dRTA (nephrocalcinosis, hypercalciuria, hypocitraturia) and proximal tubular dysfunction (hyperuricosuria, impaired tubular phosphate reabsorption and proteinuria). Discussion: Metabolic acidosis, hypercalciuria, hypocitraturia, tubular phosphate reabsorption and growth retardation in the patient improved with alkali therapy.