Effects of epigallocatechin-3-gaRate (EGCG) on a scleroderma model of fibrosis

Kocak A., Harmanci D., Birlik M., SARIOĞLU S., YILMAZ O., ÇAVDAR Z., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.43, sa.4, ss.464-473, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1515/tjb-2017-0185
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.464-473
  • Anahtar Kelimeler: BLM induced Scleroderma, EGCG, Fibrosis, TGF-beta, MMPs, BLEOMYCIN-INDUCED SCLERODERMA, REAL-TIME PCR, SYSTEMIC-SCLEROSIS, ANIMAL-MODEL, GREEN TEA, GROWTH-FACTOR, COLLAGEN PRODUCTION, SKIN FIBROBLASTS, HEPATIC-FIBROSIS, GENE-EXPRESSION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: The aim of the present study was to evaluate the potential protective effects of epigallocatechin-3-gallate (EGCG) on fibrosis in bleomycin induced scleroderma model.