ACTA ONCOLOGICA, vol.43, pp.9-12, 2004 (SCI-Expanded)
Over 80% of patients undergoing radiation of the upper hemibody, including the upper abdomen, will develop symptoms of nausea and vomiting (1). However, the impact and extent of radiation-induced nausea and vomiting (RINV) is often underestimated, particularly in terms of prolonged fractionated radiotherapy. This treatment modality, which can involve up to 40 fractions over 6-8 weeks, may result in nausea and vomiting symptoms lasting over several weeks, with a prolonged effect on patients' quality of life. Indeed, nausea and vomiting are still rated by patients as some of the most feared symptoms of cytotoxic treatment, and uncontrolled symptoms may lead to delay or refusal of future therapy (2).