An extremely rare side effect of ranitidine: junctional rhythm

Dedeoglu E., Uzun A., Bayram B., Cevik E., Arslan D.

HONG KONG JOURNAL OF EMERGENCY MEDICINE, cilt.18, sa.4, ss.232-234, 2011 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1177/102490791101800407
  • Dergi Adı: HONG KONG JOURNAL OF EMERGENCY MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.232-234
  • Anahtar Kelimeler: Bradycardia, histamine, histamine H2 antagonists, ranitidine hydrochloride, INDUCED BRADYCARDIA
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Ranitidine is a H2 receptor blocker and rarely cause bradycardia. A 28 years old male patient attended the emergency department for urticaria. He was given 45 mg of phenyramine and 50 mg of ranitidine intravenously. He then complained of dizziness and developed bradycardia and hypotension. Electrocardiogram detected junctional bradycardia rhythm. He was given 0.5 mg atropine intravenously and his rhythm then returned to normal. His symptoms subsided and the blood pressure improved. Ranitidine is a frequently used medication and this case illustrated a rare but serious side-effect of the medication. (Hong Kong j.emerg.med. 2011;18:232-234)