HIGH LIPOCALIN-2 EXPRESSION INCREASES PEMETREXED SENSITIVITY IN PATIENTS WITH LUNG ADENOCARCINOMA

Ahci S., ÇIRAK Y., Adali Y.

ACTA MEDICA MEDITERRANEA, cilt.37, sa.1, ss.495-500, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.19193/0393-6384_2021_1_77
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Sayfa Sayıları: ss.495-500
  • Anahtar Kelimeler: Cancer, lung, Lipocalin-2, pemetrexed, predictive, prognostic, GELATINASE-ASSOCIATED LIPOCALIN, UP-REGULATION, CANCER, NGAL, PROTEIN, GROWTH, DIFFERENTIATION, OVEREXPRESSION, ANGIOGENESIS, METASTASIS
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Introduction: The aim of this study is to determine the expression level of lipocalin-2 protein in human lung adenocarcinom tissues and to evaluate the relationship between its expression levels and clinicopathological parameters, including response to pemetrexed, degree of tumor differentiation, driver mutation status, progression free survival (PFS) and overall survival (OS).