Practical Approaches to the Determination of the Sample Size in Clinical Studies

DEMİREL N., GÜRLER S.

KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, cilt.16, sa.2, ss.205-211, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2010
  • Dergi Adı: KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.205-211
  • Anahtar Kelimeler: Sample size, Randomized controlled trial, Statistical data analysis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The problem of sample size determination is an important and generally difficult step of planning the statistical part of a clinical study. In this paper, some suggestions are made for determining the sample size in a successful and meaningful way. In order to design a high-quality clinical study with reliable results, practical tables and guiding clues are presented for sample size determination of t-tests for paired and independent samples.