Beneficial effects of pentoxifylline pretreatment in non-heart-beating donors in rats

Astarcioglu H., Karademir S., ÜNEK T., Ozer E., Menekay S., Coker A., ...Daha Fazla

TRANSPLANTATION, cilt.69, sa.1, ss.93-98, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 1
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1097/00007890-200001150-00017
  • Dergi Adı: TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.93-98
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Background, Pentoxifylline (PTX) pretreatment of recipients was shown to protect against liver graft failure from ischemia-reperfusion injury after orthotopic rat liver transplantation. It has also been shown that PTX protects against normothermic ischemia-reperfusion injury to the liver in lobar ischemia model in the rat. Whether PTX can benefit the liver procured from non-heart-beating donors (NHBDs) with up to 9 hr of cold ischemia is unknown.