Tuberculous pleurisy after tumour necrosis factor-a antagonist usage: Case report

Akoglu S., Babayigit C., Karazincir S., BALCI A., HANTA İ.

TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX, vol.56, no.4, pp.448-452, 2008 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 4
  • Publication Date: 2008
  • Journal Name: TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.448-452
  • Keywords: Tumour necrosis factor, TNF antagonist, infliximab, tuberculosis
  • Dokuz Eylül University Affiliated: No

Abstract

A thirty-six year old male patient presented with dyspnea, right-sided chest pain, night sweats and intermittent fever. He has a history of ankylosing spondylitis treated with tumour necrosis factor-alpha (TNF-alpha) antagonist (infliximab). Computed tomography of the chest showed mediastinal lymphadenopathy, right-sided pleural effusion, and atelectasis. The pleural fluid was exudative with lymphocyte dominance. Closed pleural biopsy was nondiagnostic. The adenosine deaminase level of the pleural fluid was 110 U/L. In light of these findings, the patient was diagnosed as tuberculous pleurisy and antituberculous treatment was given. After one month, pleural fluid was markedly reduced.