Comparison of disk diffusion, E-test and broth microdilution test in determination of susceptibility of Aspergillus species to amphotericin B, itraconazole and voriconazole

ÖZKÜTÜK A. A., Ergon C., Metin D. Y., Yucesoy M., Polat S. H.

JOURNAL OF CHEMOTHERAPY, vol.20, no.1, pp.87-92, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1179/joc.2008.20.1.87
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.87-92
  • Keywords: Aspergillus spp., antifungal susceptibility testing, CLSI M38-A, E-test, disk diffusion, amphotericin B, itraconazole, voriconazole, IN-VITRO SUSCEPTIBILITY, ANTIFUNGAL AGENTS, CANDIDA SPP., ETEST METHOD, POSACONAZOLE, FUMIGATUS, RESISTANCE, AGAR
  • Dokuz Eylül University Affiliated: Yes


In response to the recent increase in Aspergillus infections, new antifungal agents have become available accompanied by studies on antifungal susceptibility tests for epidemiological follow-up. The aim of this study was to compare the efficacy of Clinical Laboratory Standards Institute (CLSI) M 38-A broth microdilution test with the disk diffusion and E-test in determining the susceptibility of Aspergillus spp. to amphotericin B, itraconazole and voriconazole.