Appearance of Primary and Secondary Glomerulonephritis: Single Centre Experience

Baştuğ V.

BANTAO JOURNAL, vol.20181628489, no.BANTAO Journal 2018; 16(2): 84-89, pp.84-89, 2018 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 20181628489 Issue: BANTAO Journal 2018; 16(2): 84-89
  • Publication Date: 2018
  • Journal Name: BANTAO JOURNAL
  • Page Numbers: pp.84-89
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction. Glomerular disease could lead to chronic kidney disease. The aim of this study is to determine the frequency of kidney biopsy proven glomerulonephritis (GN) to create better database in Turkey. Methods. We evaluated 1273 native kidney biopsies from 2008 to 2017. Renal disease were divided into five major categories: primary GN, secondary GN, tubulointerstitial nephropathies (TIN), vascular nephropathies (VN) and acute tubular necrosis (ATN). Results. 756(59.4%) patients had primary GN, 353 (27.7%) patients had secondary GN, 101(7.9%) patients had TIN, 32(2.5%) patients had VN and 31(2.4%) patients had ATN. While, the most frequent pathological diagnosis was focal segmental glomerulosclerosis (FSGS) (31.35%), followed by membranous GN (27.65%) in primary glomerulonephritis, amyloidosis (27.2%) was the most frequent pathological diagnosis followed by systemic lupus erythematosus (SLE) (20.68%) in secondary glomerulonephritis. FSGS is the most common kidney pathology in younger than 50 years old (18-30 years old, 22% and 31-50 years old, 20%). Membranous glomerulonephritis (MGN) is the most common kidney pathology after the ages 50 years old (50-64 years old, 20% and >65 years old, 17%). Conclusion. FSGS is the most common primary GN in Turkish population and the frequency is gradually increasing.