Intra-amniotic administration of urinary trypsin inhibitor preserves intestinal contractility in meconium induced intestinal damage in chick embryos with gastroschisis.

Karakus, Osman; ATEŞ, OĞUZ; Murat, NERGİZ; HAKGÜDER, FAİKA; OLGUNER, MUSTAFA; Solmaz, Bora; ÖZER, ERDENER; Gidener, Sedef; Akgur, Feza

doi:10.1016/j.jpedsurg.2012.10.002

Intra-amniotic administration of urinary trypsin inhibitor preserves intestinal contractility in meconium induced intestinal damage in chick embryos with gastroschisis.

Karakus O. Z., ATEŞ O., Murat N., HAKGÜDER F. G., OLGUNER M., Solmaz B., ...More

Journal of pediatric surgery, vol.48, no.7, pp.1495-8, 2013 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 48 Issue: 7
Publication Date: 2013
Doi Number: 10.1016/j.jpedsurg.2012.10.002
Journal Name: Journal of pediatric surgery
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1495-8
Keywords: Gastroschisis, Intestinal contractility, Intestinal damage, Urinary Trypsin Inhibitor
Dokuz Eylül University Affiliated: Yes

Abstract

Background: Intestinal damage causes intestinal dysmotility in gastroschisis. Urinary trypsin inhibitor (UTI) has been shown to prevent intestinal damage in chick embryos with gastroschisis. The effect of intra-amniotic administration of UTI on intestinal motility in gastroschisis has not been investigated.