Effect of lithium on phosphoinositide metabolism in human brain: A proton decoupled P-31 magnetic resonance spectroscopy study


Yildiz A., Demopulos C., Moore C., Renshaw P., Sachs G.

BIOLOGICAL PSYCHIATRY, vol.50, no.1, pp.3-7, 2001 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 1
  • Publication Date: 2001
  • Doi Number: 10.1016/s0006-3223(01)01069-1
  • Journal Name: BIOLOGICAL PSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3-7
  • Keywords: lithium, inositol monophosphatase, proton decoupled P-31 MRS, inositol depletion, MOOD-STABILIZING AGENTS, SIGNAL-TRANSDUCTION PATHWAYS, MANIC-DEPRESSIVE ILLNESS, INOSITOL METABOLISM, INVIVO P-31, MYOINOSITOL, MODULATION, MECHANISM, SPECTRA, CNS
  • Dokuz Eylül University Affiliated: No

Abstract

Background: The objective of our study was to evaluate whether lithium increases brain phosphomonoester (PME) levels in human subjects.