Resveratrol Protects and Restores Endothelium-Dependent Relaxation in Hypercholesterolemic Rabbit Corpus Cavernosum.

Murat N., Korhan P., Kizer O., Evcim S., Kefi A., Demir O., ...Daha Fazla

The journal of sexual medicine, cilt.13, sa.1, ss.12-21, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jsxm.2015.12.002
  • Dergi Adı: The journal of sexual medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.12-21
  • Anahtar Kelimeler: Resveratrol, Erectile Dysfunction, Hypercholestrolemia, NITRIC-OXIDE SYNTHASE, INDUCED ERECTILE DYSFUNCTION, VASCULAR RISK-FACTORS, OXIDATIVE STRESS, NADPH OXIDASE, SMOOTH-MUSCLE, GROWTH-FACTOR, RAT MODEL, GENE-THERAPY, RED WINE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: Oxidative stress dependent-decrease in nitric oxide (NO) bioavailability plays an integral role in hypercholesterolemia-induced erectile dysfunction (ED). Resveratrol has been demonstrated to exert beneficial effects against oxidative stress and improve NO bioavailability.