Resveratrol Protects and Restores Endothelium-Dependent Relaxation in Hypercholesterolemic Rabbit Corpus Cavernosum.


Murat N., Korhan P., Kizer O., Evcim S., Kefi A., Demir O., ...More

The journal of sexual medicine, vol.13, no.1, pp.12-21, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jsxm.2015.12.002
  • Journal Name: The journal of sexual medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.12-21
  • Keywords: Resveratrol, Erectile Dysfunction, Hypercholestrolemia, NITRIC-OXIDE SYNTHASE, INDUCED ERECTILE DYSFUNCTION, VASCULAR RISK-FACTORS, OXIDATIVE STRESS, NADPH OXIDASE, SMOOTH-MUSCLE, GROWTH-FACTOR, RAT MODEL, GENE-THERAPY, RED WINE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Introduction: Oxidative stress dependent-decrease in nitric oxide (NO) bioavailability plays an integral role in hypercholesterolemia-induced erectile dysfunction (ED). Resveratrol has been demonstrated to exert beneficial effects against oxidative stress and improve NO bioavailability.