Is there a relationship between gouty arthritis and Mediterranean fever gene mutations?


SARI İ., Simsek I., Tunca Y., Kisacik B., Erdem H., Pay S., ...More

REVISTA BRASILEIRA DE REUMATOLOGIA, vol.55, no.4, pp.325-329, 2015 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1016/j.rbre.2014.10.008
  • Journal Name: REVISTA BRASILEIRA DE REUMATOLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
  • Page Numbers: pp.325-329
  • Keywords: Gouty arthritis, MEFV protein, Familial Mediterranean fever, MEFV MUTATIONS, DISEASE, FREQUENCY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Gouty arthritis and familial Mediterranean fever share some clinical and pathological features such as being classified as auto-inflammatory disease, association with inflammasome, short-lived intermittent arthritis, and good response to colchicine and anti-interleukin-1 treatments. As Mediterranean fever gene is the causative factor of familial Mediterranean fever, we aimed to investigate the prevalence of Mediterranean fever gene mutations and their effect on disease manifestations in Turkish gouty arthritis patients.