Is there a relationship between gouty arthritis and Mediterranean fever gene mutations?

SARI İ., Simsek I., Tunca Y., Kisacik B., Erdem H., Pay S., ...Daha Fazla

REVISTA BRASILEIRA DE REUMATOLOGIA, cilt.55, sa.4, ss.325-329, 2015 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 55 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.rbre.2014.10.008
  • Dergi Adı: REVISTA BRASILEIRA DE REUMATOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.325-329
  • Anahtar Kelimeler: Gouty arthritis, MEFV protein, Familial Mediterranean fever, MEFV MUTATIONS, DISEASE, FREQUENCY
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Gouty arthritis and familial Mediterranean fever share some clinical and pathological features such as being classified as auto-inflammatory disease, association with inflammasome, short-lived intermittent arthritis, and good response to colchicine and anti-interleukin-1 treatments. As Mediterranean fever gene is the causative factor of familial Mediterranean fever, we aimed to investigate the prevalence of Mediterranean fever gene mutations and their effect on disease manifestations in Turkish gouty arthritis patients.