Akademisyen Kitabevi, Ankara, 2025
Vitamin B12 deficiency, particularly when associated with pernicious anemia, holds significant clinical importance not only due to its hematological consequences but also because of its neurological and systemic effects. For many years, parenteral administration of vitamin B12 was considered the only reliable treatment option. However, this approach posed challenges for both physicians and patients, as the requirement for regular injections often reduced treatment adherence. In recent years, clinical studies have demonstrated that high-dose oral vitamin B12 therapy can also serve as an effective and reliable alternative.