Meta-analysis of longitudinal studies of cognition in bipolar disorder: comparison with healthy controls and schizophrenia

BORA İ. E., Ozerdem A.

PSYCHOLOGICAL MEDICINE, cilt.47, sa.16, ss.2753-2766, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 47 Sayı: 16
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1017/s0033291717001490
  • Dergi Adı: PSYCHOLOGICAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Sayfa Sayıları: ss.2753-2766
  • Anahtar Kelimeler: Bipolar disorder, cognition, longitudinal, mania, schizophrenia, 5-YEAR FOLLOW-UP, I DISORDER, EUTHYMIC PATIENTS, OLDER-ADULTS, METABOLIC SYNDROME, IMPAIRMENT, PERFORMANCE, DEFICITS, LITHIUM, ONSET
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background Bipolar disorder (BP) is associated with significant cognitive impairment. Recent evidence suggests that cognitive deficits are already evident after first-episode mania. However, it is not clear whether BP is associated with further decline in cognitive functions in individuals with established illness. Aim of this meta-analytic review was to examine longitudinal neurocognitive changes in BP and to compare trajectory of cognitive deficits in BP with schizophrenia and healthy controls.