Leptospirosis is the most common bacterial zoonosis globally, especially in
tropical and temperate regions with heavy rainfall. Infection into humans occurs
in direct contact with the urine of the sick animals' contact with the environment
contaminated with urine. The clinical spectrum of leptospirosis is quite broad.
It is subclinical in 90% of cases. Multiple organ failure, especially kidney, liver,
and lung, can be seen in 5-10% of cases [1-2]. Weil's disease is the most severe
form of leptospirosis. It progresses with liver dysfunction, acute renal failure,
thrombocytopenia, and fever; If left untreated, it can be fatal at 1-5% . In our
case, a 60-year-old patient with fever, hyperbilirubinemia, acute renal failure, and
thrombocytopenia will be discussed.