The dosage-dependent prenatal caffeine exposure adversely affects levels of integrin alpha V beta 3 and MMP-9 in a rat model of embryo implantation

Yilmaz F., Tekmen I.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.121, sa.9, ss.648-655, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 121 Sayı: 9
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4149/bll_2020_105
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.648-655
  • Anahtar Kelimeler: caffeine, embryo implantation, integrin, MMP-9, MUCIN 1, PREGNANCY, EXPRESSION, UTERUS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

OBJECTIVE: In the pregnancy period, it is recommended to limit the consumption of caffeine. However, the mechanisms of caffeine effect during pregnancy are not fully known. In our study, we aimed to investigate the effect of prenatal caffeine consumption on the embryonic implantation in rats as well as shed light on the relationship between the molecules and implantation stages.