Exploring at the molecular level the effects of blood and blood-insulin cardioplegias used during open-heart surgeries on myocardial prevention

Guzleoglu M., Catalyurek H., Oktay G., ALTUN Z. S., Silistireli E., Sariosmanoglu N., ...Daha Fazla

JOURNAL OF CARDIOVASCULAR SURGERY, cilt.49, sa.6, ss.809-816, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 6
  • Basım Tarihi: 2008
  • Dergi Adı: JOURNAL OF CARDIOVASCULAR SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.809-816
  • Anahtar Kelimeler: Cardiopulmonary bypass, Heart arrest, induced, Cardiac surgical procedures, SOLUBLE ADHESION MOLECULES, PYRUVATE-DEHYDROGENASE, REPERFUSION, INJURY, STIMULATION, METABOLISM, ACTIVATION, EXPRESSION, RELEASE
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aim. The aim of this study was to measure the changes in the levels of soluble adhesion molecules involved in acute inflammation during ischemia-reperfusion in adults who underwent open-heart surgery using blood and blood-insulin cardioplegia and to examine the differences in tissue damage at the molecular level as a consequence of insulin's effect on myocardial energy metabolism.