Liver function abnormalities, clinical profile, and outcome in acute decompensated heart failure

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Nikolaou M., Parissis J., YILMAZ M. B., Seronde M., Kivikko M., Laribi S., ...More

EUROPEAN HEART JOURNAL, vol.34, no.10, pp.742-749, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 10
  • Publication Date: 2013
  • Doi Number: 10.1093/eurheartj/ehs332
  • Journal Name: EUROPEAN HEART JOURNAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.742-749
  • Keywords: Heart failure, Liver, Prognosis, Inotropic agents, CARDIORENAL SYNDROME, HYPOXIC HEPATITIS, MORTALITY, DYSFUNCTION, CONGESTION, LEVOSIMENDAN, DOBUTAMINE, DIAGNOSIS, TRIAL
  • Dokuz Eylül University Affiliated: No

Abstract

The aim of this study was to assess the prevalence of abnormal liver function tests (LFTs) and the associated clinical profile and outcome(s) in acute decompensated heart failure (ADHF) patients. Alteration in LFTs is a recognized feature of ADHF, but prevalence and outcomes data from a broad contemporary cohort of ADHF are scarce and the mechanism(s) of ADHF-induced cholestasis is unknown.